نتایج جستجو برای: modifying therapies

تعداد نتایج: 132966  

2014
Annette Wundes Roxanna N Pebdani Dagmar Amtmann

Pregnancy in multiple sclerosis (MS) is considered safe for both the woman and the child. Nevertheless, pregnancy issues in MS are complex both from a patient's and a provider's perspective. In an anonymous survey, 28 healthcare providers in the United States reported on the management of multiple sclerosis (MS) during pregnancy. Participants were asked about their recommendations to patients a...

2013
Dijana Novakovic Marco Feligioni Sergio Scaccianoce Alessandra Caruso Sonia Piccinin Chiara Schepisi Francesco Errico Nicola B Mercuri Ferdinando Nicoletti Robert Nisticò

Alzheimer's disease, which is characterized by gradual cognitive decline associated with deterioration of daily living activities and behavioral disturbances throughout the course of the disease, is estimated to affect 27 million people around the world. It is expected that the illness will affect about 63 million people by 2030, and 114 million by 2050, worldwide. Current Alzheimer's disease m...

Journal: :The Journal of clinical investigation 2013
Roger A Barker Mark Stacy Patrik Brundin

Translating new findings in the laboratory into therapies for patients is a slow and expensive process. The development of therapies for neurodegenerative diseases is further complicated by the difficulty in determining whether the drug truly retards the slow degenerative process or provides only symptomatic benefit. In this issue, Aviles-Olmos et al. describe a first in Parkinson's disease (PD...

Journal: :Swiss medical weekly 2016
Matthias Naegele Andreas J Flammer Frank Enseleit Frank Ruschitzka

Heart failure with reduced ejection fraction (HFrEF) is a common cardiovascular condition with a significant individual and societal burden. Although it was previously known as a palliative condition, medical drug therapies that were developed in the last four decades significantly reduced morbidity and mortality of the disease. The cornerstone of HFrEF therapy remains the blockade of the renin...

Journal: :E3S web of conferences 2021

Alzheimer's disease (AD) is a growing global health crisis, however, there are currently very few effective treatments for it. All existent serve only to ameliorate the symptoms of AD instead curing With deepening pathology in recent years, have been many studies and clinical trials that aim discover new disease-modifying therapies. Nanoparticle drug delivery platform promising path its high pe...

Journal: : 2023

The literature review provides an update on recent advances in antiepileptic pharmacotherapy. article considers the mechanisms of action drugs, range efficacy, side effects and enzyme-inducing properties, potential teratogenicity.
 A revealed some problems patients with epilepsy remaining unresolved to this day. Despite increase number anticonvulsants years, one-third are pharmacoresistant...

Journal: :galen medical journal 0
sadegh izadi clinical neurology research center, shiraz university of medical sciences, shiraz, iran. maryam sharifian 1 clinical neurology research center, shiraz university of medical sciences, shiraz, iran. 2 student research committee, shiraz university of medical sciences, shiraz, iran. alireza nikseresht clinical neurology research center, shiraz university of medical sciences, shiraz, iran. shima rafiee student research committee, shiraz university of medical sciences, shiraz, iran.

background: multiple sclerosis (ms) is the most common demyelinating and inflammatory disease of the central nevus system especially in young adults, but in a subgroup of patients the first clinical symptoms present after the age of 50. this clinical presentation is defined as late-onset multiple sclerosis (loms). the incidence and prevalence of ms including loms vary geographically. the aim of...

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