Single-cell omics technologies help to reveal the differential use of genomic information different cell types composing plant species, during differentiation, and in response environmental stresses. Accessing high-resolution molecular is important better disclose biological function each gene mechanisms controlling their expression and, ultimately, develop new strategies enhance physiological ...

Gene expression controls the cellular differentiation and morphogenesis for body organisation. Every species has different unique patterns this is influenced by certain group of genes called as homeobox genes. Molecular events are involved in tooth development process or odontogenesis also controlled It was first identified fruit fly Drosophila Melanogaster.

introduction: it is well known that glycoconjugates on the cell surface of embryonic cells as well as extracellular matrix (ecm) are involved in many developmental phenomena including cell differentiation and maturation. these molecular events have not received proper attention during pituitary cell differentiation. the purpose of this study was to investigate glycoconjugate distribution on cel...

Bone regeneration is a process that involves several molecular mediators, such as growth factors, which directly affect the proliferation, migration and differentiation of bone-related cells. The osteogenic growth peptide (OGP) and its C-terminal pentapeptide OGP(10-14) have been shown to stimulate the proliferation, differentiation, alkaline phosphatase activity and matrix mineralization of os...

Recent studies suggest that cells make stochastic choices with respect to differentiation or division. However, the molecular mechanism underlying such stochasticity is unknown. We previously proposed that the timing of vertebrate neuronal differentiation is regulated by molecular oscillations of a transcriptional repressor, HES1, tuned by a post-transcriptional repressor, miR-9. Here, we compu...

We have employed the hybrid hammerhead ribozyme-based gene discovery system for identification of genes functionally involved in muscle differentiation using in vitro myoblast differentiation assay. The major muscle regulatory genes (MyoD1, Mylk, myosin, myogenin, and Myf5) were identified endorsing the validity of this method. Other gene targets included tumor suppressors and cell cycle regula...

Postnatal neural progenitor cells of the enteric nervous system are a potential source for future cell replacement therapies of developmental dysplasia like Hirschsprung's disease. However, little is known about the molecular mechanisms driving the homeostasis and differentiation of this cell pool. In this work, we conducted Affymetrix GeneChip experiments to identify differences in gene regula...

The progression of progenitors to oligodendrocytes requires proliferative arrest and the activation of a transcriptional program of differentiation. While regulation of cell cycle exit has been extensively characterized, the molecular mechanisms responsible for the initiation of differentiation remain ill-defined. Here, we identify the transcription factor Yin Yang 1 (YY1) as a critical regulat...

paris polyphylla smith var. yunnanensis (liliaceae) is an important traditional medicinal plant of the yunnan province in china. however, the genomic information regarding this plant is limited. to further understand its molecular background, we conducted illumina hiseq 2000 second-generation sequencing of this plant species. approximately 30,198,679 reads with an average length of 202 bases we...