نتایج جستجو برای: molecular dynamics simulations

تعداد نتایج: 1198812  

Journal: :Proceedings of the National Academy of Sciences 2018

Journal: :Human Genetics 2021

A non-negligible proportion of human pathogenic variants are known to be present as wild type in at least some non-human mammalian species. The standard explanation for this finding is that molecular mechanisms compensatory epistasis can alleviate the mutations’ otherwise effects. Examples compensated have been described literature but interacting residue(s) postulated play a role rarely ascert...

The 25-35 fragment of the amyloid β (Aβ) peptide is a naturally occurring proteolytic by-product of its larger parent molecule that retains the amyloid characteristics and toxicity of the full length parent molecule. Aggregation of this peptide occurs rapidly in aqueous solutions and thus characterization of its folding process is very difficult. In the present study, early stages of Aβ(25–35) ...

Journal: :Applied Physics A Materials Science & Processing 1996

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