1 The School of Physics and The Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN), Trinity College Dublin, Dublin 2, Ireland 2 Toronto Western Hospital, UHN, 399 Bathurst Street, Toronto, ON M5T 2S8, Canada M5T 2S8 3 Institut Jacques Monod, CNRS-Université Paris Diderot, 75205 Paris Cedex 13, France 4 Department of Chemistry, University of Basel, Klingelbergstrasse 80, 4056...

2014 The high field magnetization data of Monod, Felner, Chouteau and Shaltiel [1] on TiBe2 are discussed in terms of a metamagnetic transition in fields about 5 T. J. Physique LETTRES 41 (1980) L-563 L-565 1 er DÉCEMBRE 1980,

We present a framework for computing the gating properties of ligand-gated ion channel mutants using the Monod-Wyman-Changeux (MWC) model of allostery. We derive simple analytic formulas for key functional properties such as the leakiness, dynamic range, half-maximal effective concentration ([EC50]), and effective Hill coefficient, and explore the full spectrum of phenotypes that are accessible...

Skolpap, W., Scharer, J.M., Douglas, P.L. and Moo-Young, M. Optimal feed rate profiles for fed-batch culture in penicillin production Songklanakarin J. Sci. Technol., 2005, 27(5) : 1057-1064 The fed-batch optimization of penicillin productivity was applied as an example of optimization algorithm verification. The objective function of this problem was to optimize penicillin productivity by dete...

11 Allosteric molecules serve as regulators of cellular activity across all domains of life. We present a general 12 theory of allosteric transcriptional regulation that permits quantitative predictions for how physiological 13 responses are tuned to environmental stimuli. To test the model’s predictive power, we apply it to the 14 specific case of the ubiquitous simple repression motif in bact...

The Jacques Monod conference "Insect Immunity in Action: From Fundamental Mechanisms of Host Defense to Resistance Against Infections in Nature," organized by Ulrich Theopold (Stockholm University, Sweden) and Dominique Ferrandon (CNRS, France), was held in May 2009 in Aussois, France. Here, we review key topics and concepts that were presented and highlight emerging trends in the field of inse...