This study aimed to compare the efficacy and safety of the classic Morrow septal myectomy with the modified procedure in treating hypertrophic obstructive cardiomyopathy (HOCM).A retrospective study was conducted to compare the outcomes of classic with modified Morrow septal myectomy in 42 patients treated from January 2005 to July 2011. Preoperative and postoperative ventricular septal thickne...

BACKGROUND Stepped wedge trials (SWTs) can be considered as a variant of a clustered randomised trial, although in many ways they embed additional complications from the point of view of statistical design and analysis. While the literature is rich for standard parallel or clustered randomised clinical trials (CRTs), it is much less so for SWTs. The specific features of SWTs need to be addresse...

background: marrow-derived mesenchymal stem cells (mscs) have been heralded as a source of great promise for the regeneration of the infarcted heart. there are no clear data as to whether or not in vitro differentiation of mscs into major myocardial cells can increase the beneficial effects of mscs. the aim of this study was to address this issue. methods: to induce mscs to transdifferentiate i...

Introduction An influential conjecture in neuroscience states that a brain organized according to principles of hierarchical predictive coding (HPC) can effectively and efficiently perform genuine Bayesian inferences, providing a neurally plausible account of how Bayesian models of cogntion may be physically implemented in the brain. However, each key subcomputation invoked in HPC potentially h...

We present a study on wavelet detection methods of neuronal action potentials (APs). Our final goal is to implement the selected algorithms on custom integrated electronics for on-line processing of neural signals; therefore we take real-time computing as a hard specification and silicon area as a price to pay. Using simulated neural signals including APs, we characterize an efficient wavelet m...

This study presents an image segmentation system that automatically segments and labels T1-weighted brain magnetic resonance (MR) images. The method is based on a combination of unsupervised learning algorithm of the self-organizing maps (SOM) and supervised learning vector quantization (LVQ) methods. Stationary wavelet transform (SWT) is applied to the images to obtain multiresolution informat...

BACKGROUND Chronic proximal hamstring tendinopathy is an overuse syndrome that is usually managed by nonoperative methods. Shockwave therapy has proved to be effective in many tendinopathies. HYPOTHESIS Shockwave therapy may be more effective than other nonoperative treatments for chronic proximal hamstring tendinopathy. STUDY DESIGN Randomized controlled clinical study; Level of evidence, ...

AIMS To study recovery of segmental wall thickening (SWT), ejection fraction (EF), and end-systolic volume (ESV) after acute myocardial infarction (AMI) in patients who underwent primary stenting with drug-eluting stents. Additionally, to evaluate the predictive value of magnetic resonance imaging (MRI)-based myocardial perfusion and delayed enhancement (DE) imaging. METHODS AND RESULTS Twent...

Recently, as demonstrated by an antiferromagnetic spin-lattice application, we have successfully extended the coupled-cluster method (CCM) to a variational formalism in which two sets of distribution functions are introduced to evaluate Hamiltonian expectation. We calculated these distribution functions by employing an algebraic scheme. Here we present an alternative calculation based on a diag...