The mammalian reovirus (MRV) genome comprises 10 double-stranded RNA (dsRNA) segments, packaged along with transcriptase complexes inside each core particle. Effects of four small molecules on transcription by MRV cores were studied for this report, chosen for their known capacities to alter RNA duplex stability. Spermidine and spermine, which enhance duplex stability, inhibited transcription, ...

Isolated cortical vein thrombosis (ICVT) is extremely rare. Only single case or small series of ICVT have been reported; clinical details are still uncertain. We report a case of isolated superficial sylvian vein thrombosis with exceedingly long cord sign. A 14-year-old female with severe sudden onset headache visited our hospital. Fluid attenuated inversion recovery and echo-planar T2(*) susce...

OBJECTIVE To evaluate the demographics, diagnosis, management, and outcomes of lateral sinus thrombosis in a pediatric population, and to propose a new treatment algorithm. METHODS Retrospective review of seven patients. RESULTS Patients averaged 7.4 years of age. They commonly presented with headache and otalgia (seven of seven patients), and nausea and vomiting (six of seven patients). Al...

BACKGROUND Recent studies using colour-coded Doppler sonography showed that chronic impaired venous drainage from the central nervous system is almost exclusively found in multiple sclerosis (MS) patients. This study aimed to investigate the intracranial and extracranial venous anatomy and the intracerebral venous flow profile in patients with MS and healthy controls using magnetic resonance ve...

This study is to explore and evaluate the efficacy and safety of local thrombolytic therapy in superior sagittal sinus in patients with severe cerebral venous sinus thrombosis during puerperium, as well as the efficacy and safety of anti-platelet aggregation treatment for preventing recurrence. Twelve patients during postpartum period with cerebral venous sinus thrombosis were received local th...

While it has been shown that the Global Optic Flow Rate (GOFR) is used in the control of self-motion speed, this study examined its relevance in the control of interceptive actions while walking. We asked participants to intercept approaching targets by adjusting their walking speed in a virtual environment, and predicted that the influence of the GOFR depended on their interception strategy. I...

With the gap between developed and developing nations remaining unclosed, post-Kyoto Protocol negotiations have run into rough waters: Developing countries insist that developed countries be committed to more ambitious targets for the second phase of the Kyoto Protocol and provide large amounts of financial or technological assistance to developing countries, while developed countries propose t...

We present the case of a 23 year old with acute onset left hemiparesis and meningeal irritation, associated with recent history of chickenpox 15 days prior. Varicella-IgG and IgM was positive in the CSF and blood along with reduced serum/CSF ratios of VZV immunoglobulins. MRV showed thrombosis (CVT) of superior sagittal, transverse, right sigmoid sinuses with haemorrhagic infarct in right front...

There is global interest in spectroscopy and the development of large diverse soil spectral libraries (SSL) to model organic carbon (SOC) monitor, report, verify (MRV) its changes. The reason that increasing SOC can improve food production mitigate climate change. However, ‘global’ modelling with such hyperdimensional SSLs do not generalise well locally, e.g. at a field scale. To address this c...

Abstract. Better monitoring, reporting, and verification (MRV) of the amount, additionality, persistence sequestered soil carbon is needed to understand best farming practices for different soils climate conditions, as well their actual benefits or cost efficiency in mitigating greenhouse gas emissions. This paper presents our Field Observatory Network (FiON) researchers, farmers, companies, ot...