Myelencephalon-specific protease (MSP) is a novel serine protease that is expressed predominantly in the nervous system. In the adult rat spinal cord, MSP mRNA expression was dramatically upregulated, in both the white and gray matter, after systemic exposure to the glutamate receptor agonist, kainic acid (KA) (Scarisbrick et al. J Neurosci 17: 8156-8168, 1997b). To determine the cell-specific ...

We construct algebraic cobordism spectra MSL and MSp. They are commutative monoids in the category of symmetric T-spectra. The spectrum MSp comes with a natural symplectic orientation given either by a tautological Thom class th ∈ MSp4,2(MSp2), a tautological Pontryagin class p MSp 1 ∈ MSp (HP) or any of six other equivalent structures. For a commutative monoid E in the category SH(S) we prove ...

Marine spatial planning (MSP) is currently practiced by almost half of the world’s nations. While some countries are working on their second, third or fourth round MSP, many going through first marine planning. Thus, there experiences to share and reflect upon. Current practices MSP show a minimum ecosystem-based approaches, which indicates need develop practice further. This paper examines com...

PURPOSE To measure perimetric sensitivity and response variability of glaucomatous patients with single-stimulus automated perimetry (SSAP) and multiple-stimulus perimetry (MSP) with verbal feedback. METHODS Frequency-of-seeing (FOS) data were collected from the same four visual field locations (normal and reduced sensitivity) in one eye of 10 glaucoma patients, using SSAP and MSP. The SSAP t...

Alcoholism is a pervasive societal problem, yet available pharmacotherapies fail to treat most sufferers. The type 1 corticotropin-releasing factor (CRF1) receptor has received much attention for its putative role in the progression to alcohol dependence, although at present its success in clinical trials has been limited. Two single-nucleotide polymorphisms in the rat Crhr1 promoter have been ...

Receptor subtypes involved in the 5-hydroxytryptamine (5-HT)-induced depression of synaptic transmission in neonatal rat spinal cords in vitro were evaluated in the absence or presence of Mg(2+) in the medium. Stimulation of a dorsal root evoked monosynaptic reflex potential (MSP) and polysynaptic reflex potential (PSP) in the segmental ventral root in Mg(2+)-free medium where the voltage-depen...

AIMS Alternative forms of cardiac resynchronization therapy (CRT), including biventricular endocardial (BV-Endo) and multisite epicardial pacing (MSP), have been developed to improve response. It is unclear which form of stimulation is optimal. We aimed to compare the acute haemodynamic response (AHR) and electrophysiological effects of BV-Endo with MSP via two separate coronary sinus (CS) lead...

BACKGROUND This study examines prevalence and correlates of multiple sexual partnerships (MSP) among women aged 15+ years in Rufiji, Kilombero, and Ulanga districts of Tanzania. MATERIALS AND METHODS Data were collected in a cross-sectional household survey in Rufiji, Kilombero, and Ulanga districts in Tanzania in 2011. From the survey, a total of 2,643 sexually active women ages 15+ years we...

We have studied the genetic polymorphism at 10 Plasmodium falciparum loci that are considered potential targets for specific antimalarial vaccines. The polymorphism is unevenly distributed among the loci; loci encoding proteins expressed on the surface of the sporozoite or the merozoite (AMA-1, CSP, LSA-1, MSP-1, MSP-2, and MSP-3) are more polymorphic than those expressed during the sexual stag...

In addition to its effects on macrophage function, macrophage-stimulating protein (MSP) is a growth and motility factor for epithelial cells. The growth and survival of epithelial cells generally require two signals, one generated by interaction with extracellular matrix via integrins, the other initiated by a growth factor. Therefore we investigated the effect of MSP on epithelial cell surviva...