Toremifene is an anti-estrogen which has been shown to be effective in the treatment of breast cancer, and is thought to be a less uterotrophic agent than tamoxifen. The risk assessment concerning endometrial cancer has been inconclusive because of its rare use up to the mid-1990s. We report a case of an adenosarcoma, which is a very rare type of uterine malignancy, after toremifene treatment f...

Malignant mixed Mullerian tumors of the cervix are very rare tumors, constituting only 0.005% of all cervical malignancies. It usually presents with abnormal vaginal bleeding in post-menopausal women. The tumor has high rates of metastasis, so careful management including surgery, chemotherapy and/or radiotherapy is done for these patients. Here, we present a case of a 47 year old woman who pre...

BACKGROUND Leiomyoma with secondary changes arising from Mullerian remnant may mimic ovarian tumor in women with Mayer-Rockitansky-Kuster-Hauser (MRKH) syndrome in patients with pelvic mass and urologic abnormalities. CASE DETAIL The patient was a 40 years old known case of MRKH, presented with lower abdominal pain and swelling for over one year. On physical examination, large pelvic mass (ab...

Insomnia merupakan masalah kesehatan yang umum terjadi pada lanjut usia. Proses penuaan menyebabkan penurunan atau perubahan kondisi fisik dan psikologis sehingga meningkatkan latensi tidur, menurunkan efisiensi serta terbangun lebih awal. Salah satu metode penyembuhan insomnia adalah dengan terapi murottal Al-Qur’an. Terapi Al-Qur’an dapat hormon-hormon stress hormon endorfin perasaan rileks b...

OBJECTIVE Cardiac autonomic dysfunction may develop in patients with polycystic ovary syndrome (PCOS). Heart rate variability (HRV) and heart rate turbulence (HRT) are used in assessing cardiac autonomic functions. The goal of this study was to compare the cardiac autonomic functions in patients with PCOS and healthy controls. To our knowledge, this is the first study evaluating cardiac autonom...

Stroke merupakan penyebab kematian paling umum kedua dan kecacatan ketiga di dunia. Secara global, sebesar 68% menderita stroke iskemik. Pasca iskemik terjadi proses neuroinflamasi yang respon alami dari sistem imunitas terhadap jaringan. Proses inflamasi berkembang menjadi tiga fase yaitu akut dimulai beberapa saat setelah terjadinya iskemik, subakut hari pasca serangan akhir pemulihan astrosi...

MAIN FINDINGS A typical male looking adolescent with a legal female gender assignment presented with haematuria. Investigations led to the diagnosis of Persistent Mullerian Duct Syndrome. The condition is indeed a rare entity that needs a multidisciplinar team management. Case hypothesis: A case of Persistent Mullerian Duct Syndrome undiagnosed at birth because karyotyping was defaulted, thus r...