نتایج جستجو برای: multi drug resistance mdr
تعداد نتایج: 1345398 فیلتر نتایج به سال:
Submit Manuscript | http://medcraveonline.com year [1]. TB is responsible for more years of healthy life lost than any other infectious disease, bar AIDS and malaria [2]. The major problem with treatment of TB however lies in lack of effective treatment methods. With the emergence of multi-drug resistant (MDR) and extensively-drug resistant (XDR) strains of M. tuberculosis the disease has becom...
BACKGROUND We conducted a first baseline survey in Jilin Province of China to determine the proportion of drug-resistant tuberculosis (TB), and to analyze risk factors associated with the emergence of drug-resistance. METHODOLOGY/PRINCIPAL FINDINGS Thirty counties in Jilin Province were randomly selected as survey sites using a stratified cluster sampling method. People enrolled in the survey...
Drug-resistant Mycobacterium tuberculosis is challenging elimination of tuberculosis (TB). We evaluated risk factors for TB and levels of second-line drug resistance in M. tuberculosis in patients in Europe with multidrug-resistant (MDR) TB. A total of 380 patients with MDR TB and 376 patients with non-MDR TB were enrolled at 23 centers in 16 countries in Europe during 2010-2011. A total of 52....
background and objectives: the prevalence of multidrug resistant pseudomonas aeruginosa is the main reason of new drugs resurgence such as colistin. the main objectives of this study were to determine the antibiotic resistance pattern and the rate of colistin resistance along with its correlation with overexpression of mexab-oprm and mexxy-oprm efflux pumps among p. aeruginosa isolates. materia...
India contributes to approximately one-third of total global tuberculosis (TB) and one-fourth all Multi-Drug Resistant TB (MDR-TB) burden respectively. The First National drug resistance survey (2014-16) showed MDRTB rates 6.19% overall 2.14% in newly diagnosed cases. With the above problem primary among cases, present study was planned find prevalence Isoniazid (INH) Rifampicin treatment naïve...
multi drug resistance(mdr) is a major problem in the treatment of cancer and hemalological malignancies. this resistance is multi factorial and is the result of decreased intra cellular drug accumulation. this is partly due to the presence of a 170kd intra membranous protein termed p-glycoprotein(p-gp) that is an energy-dependent efflux pump which has increased expression on drug-resistance cel...
The pathogenesis of antiepileptic drug (AED) resistance is multifactorial. However, most candidate gene association studies typically assess the effects of candidate genes independently of each other, which is partly because of the limitations of the parametric-statistical methods for detecting the gene-to-gene interactions. A total of 200 patients with drug-resistant epilepsy and 200 patients ...
Multi-cycle chemotherapy is commonly used in the clinic, while the phenomena of enrichment of cancer stem cells (CSCs) and enhanced multi-drug resistance (MDR) are commonly involved. This research was designed for evaluating this successive administration. Chitosan oligosaccharide-g-stearic acid (CSOSA) polymer was used as the drug delivery system (DDS) to perform tri-cycle chemotherapy on a ne...
antibiotic resistance is a phenomenon in which antibiotic used to treat bacteria becomes useless due to resistance mechanism. increased drug resistance and occurrence of multiple drug resistance in bacteria specificity nosocomial and urinary tract infection bacteria has reduced the possibilities of treating these infectious diseases. efflux pumps are one of the major mechanism of mdr in bacteri...
enterococci are gram positive and catalase- negative cocci that are found in the gastrointestinal tract of mammals and birds, and are readily isolated from soil, surface and waters. the aim of this study was to discriminate between enterococcus isolates based on repetitive element sequence based –pcr (rep-pcr) with the boxa2r primer and their antibiotics profile. enterococci isolates were obtai...
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