Today, emerging and increasing resistance to antibiotics has become a threat to public health worldwide. Antimicrobial peptides have unique action mechanisms making them an attractive therapeutic prospect to be applied against resistant bacteria. However, the major drawback is related with their high hemolytic activity which cancels out the safety requirements for a human antibiotic. Therefore,...

This paper is devoted to the search for Choquet-optimal solutions in multicriteria combinatorial optimization with application to spanning tree problems and knapsack problems. After recalling basic notions concerning the use of Choquet integrals for preference aggregation, we present a condition (named preference for interior points) that characterizes preferences favouring well-balanced soluti...

Our purpose in this paper is to show the integration properties of the intuitionistic fuzzyvalued Choquet integrals, by which improper applications of this type of Choquet integral in the multicriteria decision making can be avoided. We first propose some important operational properties of intuitionistic fuzzy values (IFVs) and give a short review of the methods of comparing IFVs in the framew...

Development and use of remediation technologies for contaminated soils and water progresses at a very fast pace and thus a large number of cleanup alternatives emerge. The selection of the most appropriate Remediation technology for the given site must be based on many, usually conflicting, criteria. To successfully apply all these criteria a multicriteria decision support system (DSS) is neede...

This paper addresses the problem of multicriteria (versus single-criterion) parametrical identification of the autonomously controlled cargo parafoil. Based on the structural identification as an initial step toward creation of an adequate model of the parafoil, a high-fidelity model including several dozens of optimization parameters has been developed. The present paper proposes the correct s...

This paper deals with multicriteria discrete-continuous problems of scheduling nonpreemptable jobs. The need for reusability and modularity leads us to build a “generic” optimisation and simulation framework, while the need to quickly generate good compromises between conflicting objectives requires the implementation of multicriteria scheduling models. This paper describes the practical possib...

The paper proposes a general framework to composite Web services selection based on multicriteria evaluation. The proposed framework extends the Web services architecture by adding, in the registry, a new Multicriteria Evaluation Component (MEC) devoted to multicriteria evaluation. This additional component takes as input a set of composite Web services and a set of evaluation criteria and gene...

We propose a unified approach to the multicriteria design of diffractive optics. A multicriteria version of the direct binary search that allows the user to adjust the compromise between the diffraction efficiency and the signal-to-noise ratio already exists. This technique has proved to be extremely powerful but also very time consuming. We extend this multicriteria approach to the iterative F...

This paper presents a method for solving the multicriteria group decision making problem in an uncertain linguistic environment. To ensure an effective aggregation of the uncertain linguistic variables in multicriteria group decision making for adequately modeling the uncertainty and imprecision of the decision making process, an uncertain linguistic Choquet integral operator is proposed. A met...

Linear convolution of particular criteria is often used as aggregated criterion in problems of multicriteria optimization. The weights of significance of partial criteria can be obtained on the basis of their ranking by experts. Mistake in expert judgments may lead to inaccuracy in determining the weights and (as a consequence) to the inaccuracy in the solution of the problem of multicriteria o...