430 www.thelancet.com Vol 372 August 9, 2008 in the general population, it is diffi cult to exclude chance as an explanation for their fi ndings. In today’s study, Vestergaard and colleagues tested the hypothesis that febrile seizures are associated with an increased risk of death, by examining mortality data from a cohort of more than 1·6 million children, including over 55 000 children with f...

OBJECTIVES To examine the degree of hippocampal atrophy in patients with temporal lobe epilepsy and proved hippocampal sclerosis to determine whether or not patients with febrile seizures have more severe hippocampal atrophy. To determine whether or not there is a relation between age of seizure onset, duration of temporal lobe epilepsy, or seizure frequency, and severity of hippocampal atrophy...

to ascertain whether lp was justifiable in cases of first simple febrile seizure, the records of128 such patients were critically reviewed in this study. it was evident that in 90% of those who received cerebrospinal fluid examination as a routine work up, lumbar puncture could have been avoided if the definition of simple febrile seizure was adhered to and the history and clinical findings wer...

OBJECTIVES American Academy of Pediatrics consensus statement recommendations are to consider strongly for infants 6 to 12 months of age with a first simple febrile seizure and to consider for children 12 to 18 months of age with a first simple febrile seizure lumbar puncture for cerebrospinal fluid analysis. Our aims were to determine compliance with these recommendations and to assess the rat...

UNLABELLED Convulsions triggered by fever are the most common type of seizures in childhood, and 20% to 30% of them have recurrence. The prophylactic treatment is still controversial, so we performed a systematic review to find out the effectiveness of continuous phenobarbital and intermittent diazepam compared to placebo for febrile seizure recurrence. METHOD Only randomized, double-blind, p...

Background and Objectives:    Febrile convulsion is one of the most common types of seizure in childhood. Its pathogenesis is unknown, so studying its cause is valuable. The purpose of this study was to determine the serum level of zinc and magnesium in children withfebrileconvulsion (F.C) (3 months to 6 years age). Patients and Methods: In this analytical case-control study, serum le...

BACKGROUND Although routine lumbar puncture (LP) is often recommended as part of the assessment of fever-associated seizures in children, accumulating evidence questions its value and reveals a decrease in its frequency. Our primary hypothesis was that children who present with a single seizure but with no clinical signs of meningism or coma do not require LP as part of initial diagnostic asses...

OBJECTIVE To evaluate the oxidative status following a seizure in children experiencing a simple febrile seizure. METHODS The cross-sectional study was conducted at Harran University, Turkey, between January and September 2011. It comprised 32 paediatric patients who, within the preceding 8 hours, had experienced a seizure due to upper respiratory tract infection and had been diagnosed with s...