In the past three years, ISMuLT has been active nationally and internationally in scientific meetings on the physiology and pathology of muscles, ligaments and tendons. This issue of Muscles, Ligaments and Tendons Journal focuses on the basic science aspects of muscles in human, in animals and in a number of in vitro models. Highlighting the structure and function of muscle tissue, starting fro...

The impact of SARS-CoV-2 infection on respiratory muscle functions is an important area recent enquiry. COVID-19 has effects the muscles. diaphragm perturbed indirectly due to mechanical-ventilation-induced-disuse, but also by direct mechanisms linked with viral infection. In this sense, a deeper understanding possible links between and alterations in structure muscles may increase success rate...

Type 6 collagen (COL6) is produced by mesenchymal stromal cells (MSC) in skeletal muscle, and its gene mutation the cause of Ullrich congenital muscular dystrophy (UCMD). To test whether COL6 supplementation has a therapeutic effect for UCMD, we conducted vivo vitro experiments using healthy induced pluripotent stem cell (iPSC)-derived MSCs (iMSCs) COL6-deficient iMSCs (KO-iMSCs). The transplan...

Determining conscious processing in unresponsive patients relies on subjective behavioural assessment. Using data from hand electromyography, the authors studied the occurrence of subthreshold muscle activity in response to verbal command, as an objective indicator of awareness in 10 disorders of consciousness patients. One out of eight vegetative state patients and both minimally conscious pat...

Malignant pathologies may be observed in the histopathological examination of patients who were operated with diagnosis myoma uteri. We aimed to investigate rates detection uterine sarcoma, smooth muscle tumor uncertain malignant potential and benign variants due Patients uteri between 2012-2018 included. without pathology compared terms their characteristics. The malignancy was encountered 39 ...

Mutations in several glycosyltransferases underlie a group of muscular dystrophies known as glycosylation-deficient muscular dystrophy. A common feature of these diseases is loss of glycosylation and consequent dystroglycan function that is correlated with severe pathology in muscle, brain and other tissues. Although glycosylation of dystroglycan is essential for function in skeletal muscle, wh...