Seventeen samples of tap water in Bangkok and 2 neighboring provinces were collected in winter and summer, concentrated and tested for mutagenic activity using the Ames Salmonella mutagenesis assay. Preliminary results demonstrated that concentrated tap water exhibited clear mutagenicity towards S. typhimurium TA100 and YG1029, but not towards TA98 and YG1024, in the absence of S9 mix, and the ...

Fine airborne respirable particulates less than 10 micrometer (PM10) are considered one of the top environmental public health concerns, since they contain polycyclic aromatic hydrocarbons (PAHs) which are among the major carcinogenic compounds found in urban air. The objective of this study is to assess the genotoxicity of the ambient PM10 collected at 11 urban sites in Jeddah, Saudi Arabia. T...

LANGOVÁ M., POLÍVKOVÁ Z., ŠMERÁK P., BÁRTOVÁ J., BÁRTA I. (2005): Antimutagenic effect of resveratrol. Czech J. Food Sci., 23: 202–208. Evidence exist from population-based and laboratory studies that some phytochemicals have protective effects against tumors or other diseases and reveal antimutagenic activity. We studied the protective effect of the plant phytoallexin resveratrol on the mutage...

Perfluorooctanoic acid (PFOA) is a perfluorinated compound ubiquitously detected in the environment, including wildlife and humans. Despite the available information, research on the cytotoxicity of PFOA in non-tumoral mammalian cells is relatively limited. In this work, two in vitro toxicity systems were employed to provide further insight into the cytotoxic and mutagenic potential of PFOA. Th...

titanium (ti) is one of the most widely used biomaterials for manufacturing dental implants. the implant surface properties strongly influence osseointegration. the aim of the present study was to in vitro investigate the characteristics of ti dental implants in terms of mutagenicity, hemocompatibility, biocompatibility, osteoinductivity and biological safety. the ames test was used to test the...

Lafoensia pacari (Lythraceae), popularly known in Brazil as "pacari", is a small tree native to the Cerrado that is used in folk medicine to treat cancer and as an anti-inflammatory and cicatrizing agent. We evaluated the genotoxic, cytotoxic, antigenotoxic, and anticytotoxic activities of an ethanol extract of L. pacari stem bark (EESB) using the Ames test and the mouse bone marrow micronucleu...