نتایج جستجو برای: mutational pressure
تعداد نتایج: 425613 فیلتر نتایج به سال:
BACKGROUND AND PURPOSE Codon and amino acid usage biases determined in numerous organisms have deciphered the architectures of their protein-coding genes to some extent. To understand the architecture of protein-coding genes of Aeromonas phages, codon and amino acid usage biases have been investigated in the protein-coding genes of the Aeromonas hydrophila phage Aeh1. METHODS In order to stud...
EGFR (Epidermal growth factor receptor) is a key driver mutation frequently isolated in lung cancers and anti-EGFR TKIs (tyrosine kinase inhibitors) have demonstrated significant improvements patient outcomes comparison to conventional chemotherapy. This study assessed the prevalence clinical of mutations among Indian NSCLC cohort. Retrospective analysis 2548 patients who underwent mutational f...
β-catenin is a multifunctional protein, acting both as a structural component of the cell adhesion machinery and as a transducer of extracellular signals. Deregulated β-catenin protein expression, due to mutations in the β-catenin gene itself or in its upstream regulator, the adenomatous polyposis coli (APC) gene, is prevalent in colorectal cancer and in several other tumor types, and attests t...
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