Avian mycobacteriosis was diagnosed in one female Mauritian Pink pigeon (Nesoenas mayeri) from a zoological collection. The bird displayed clinical symptoms of apathy, loss of body weight, ruffled feathers and diarrhoea. Necropsy revealed nodular lesions in the internal organs. Mycobacterium avium subsp. avium was isolated and also directly detected using qPCR in the female’s liver. Avian mycob...

In cattle, Mycobacterium avium subsp. paratuberculosis infection is primarily mediated through M cells overlying Peyer's patches (PP) in the ileum. The capacity of M. avium subsp. paratuberculosis to invade ileal PP (IPP) versus discrete PP in the jejunum (JPP) and subsequent differences in mucosal immune responses were investigated. Intestinal segments were surgically prepared in both mid-jeju...

We previously isolated and sequenced two genomic segments of Mycobacterium avium subsp. paratuberculosis, namely, f57, a species-specific sequence, and the p34 gene, coding for a 34-kDa antigenic protein. Comparison of sequences upstream of the p34 open reading frame (us-p34) from M. avium subsp. paratuberculosis and M. tuberculosis showed a 79-base deletion in M. tuberculosis. Sequence analysi...

background and objectives: pigeons are extensively kept for homing and racing purposes in iran. the main objective of this study was to investigate dissemination of m. avium subsp. avium (maa) in pigeon aviaries in tabriz, north-western iran. materials and methods: postmortem pathologic specimens from thirty-nine out of 140 birds collected from private flocks (n = 3), were subjected to bacteria...

The longstanding assumption that calves of more than 6 months of age are more resistant to Mycobacterium avium subspecies paratuberculosis (MAP) infection has recently been challenged. In order to elucidate this, a challenge experiment was performed to evaluate age- and dose-dependent susceptibility to MAP infection in dairy calves. Fifty-six calves from MAP-negative dams were randomly allocate...

Mycobacterium avium subsp. (MAA) is the main tuberculosis pathogen of poultry and wild birds. MAA can also infect mammals such as pigs, cattle, horses pose a threat to people with low immunity. Here, we describe first identification strain HJW isolated from cow in Jilin Province, China. The isolate was completely sequenced phylogenetic analysis its relationship members complex (MAC) performed. ...

Mycobacterium avium subsp. paratuberculosis has been incriminated as a cause of Crohn's disease (CD); however, studies to date have been relatively small and generally only used a single diagnostic assay. The objective of the study was to reexamine the association of M. avium subsp. paratuberculosis and CD using multiple diagnostic tests. Five methods were used to detect M. avium subsp. paratub...

Pavlas, M.: Heat Resistance and Vinllence ofSerovars of the Mycobacterium avium Complex. Acta vet. Bmo 1997,66: 249-252. Heat resistance and virulence tested in chickens were investigated in 151 strains classified with the Mycobacterium avium complex. The highest differences in heat resistance between virulent and avirulent strains were found at 2-h exposure to 60°C. Under such conditions, 92% ...

The effectiveness of high-temperature, short holding time (HTST) pasteurization and homogenization with respect to inactivation of Mycobacterium avium subsp. paratuberculosis was evaluated quantitatively. This allowed a detailed determination of inactivation kinetics. High concentrations of feces from cows with clinical symptoms of Johne's disease were used to contaminate raw milk in order to r...

"Mycobacterium avium subsp. hominissuis" is a robust and pervasive environmental bacterium that can cause opportunistic infections in humans. The bacterium overcomes the host immune response and is capable of surviving and replicating within host macrophages. Little is known about the bacterial mechanisms that facilitate these processes, but it can be expected that surface-exposed proteins play...