نتایج جستجو برای: myocardial ischemia
تعداد نتایج: 208325 فیلتر نتایج به سال:
A 75-year-old woman who had previously been diagnosed with Bland-White-Garland syndrome was admitted to our hospital for acute decompensated heart failure (ADHF). Following her recovery from ADHF, pharmacologic stress myocardial scintigraphy revealed myocardial ischemia in the basal anterior area of the left ventricle. Moreover, myocardial scintigraphy showed the improvement of the myocardial i...
Background In stable coronary artery disease (CAD), accurate ischemia detection enables targeted revascularization, which improves clinical outcomes. Myocardial blood volume (MBV) may be a better ischemia marker than myocardial blood flow. Adenosine stress and rest T1-mapping is a novel gadolinium-free CMR technique that reflects changes in MBV through its water content. We hypothesized that di...
The relationship between QT dispersion and myocardial ischemia is still controversial. Therefore, we aimed to investigate the relationship between QTd and the severity and extent of myocardial ischemia. In this cross-sectional study, 141 patients having symptoms of CAD who referred to our medical center during 2009-2010, and were examined with myocardial isotope scan and ECG, were enrolled. Bas...
BACKGROUND Myocardial ischemia is associated with alterations in cardiac metabolism, resulting in decreased fatty acid oxidation and increased lipid accumulation. Here we investigate how myocardial lipid content and dynamics affect the function of the ischemic heart, and focus on the role of the lipid droplet protein perilipin 5 (Plin5) in the pathophysiology of myocardial ischemia. METHODS A...
UNLABELLED We evaluated the effect of aprotinin, administered before the onset of acute regional myocardial ischemia, on reversible contractile dysfunction induced by ischemia and reperfusion in pentobarbital-anesthetized dogs. Animals were randomized to receive either aprotinin 30,000 kallikrein inactivator units (KIU)/kg and 7000 KIU x kg(-1) x hr(-1) (n = 8) or equivalent volumes of 0.9% sod...
Abnormalities of coronary artery, congenital or acquired, are rare in the pediatric population, but they frequently present unexpectedly. They may result in life-threatening conditions if unrecognized; however, in infants and children, preclinical coronary abnormalities usually do not present with the typical clinical manifestations seen in adults with myocardial ischemia. Timely diagnosis of s...
We have previously demonstrated that simvastatin attenuates myocardial cell necrosis after acute myocardial ischemia and reperfusion via induction of endothelial cell NO synthase. However, it remains unknown whether the cardioprotective effects of statins can persist after extended periods of reperfusion. Furthermore, it is unknown whether simvastatin therapy can attenuate postischemic cardiac ...
The first case of novel corona virus disease (COVID-19) was reported in China and undoubtedly today this has rapidly crossed borders, infecting people throughout the world. There are heaps complications related to COVID-19 namely acute respiratory failure, liver kidney injury, bacterial fungal infections, septic shock. Vascular thrombosis is another burden that pilling on load its complications...
BACKGROUND Although oxygen inhalation therapy has long been used in the treatment of acute myocardial ischemia, experimental evidence that increased arterial PO2 has any beneficial effect in the absence of hypoxemia is equivocal. In this study, we used a swine model of subendocardial myocardial ischemia to determine the effects of arterial hyperoxia on regional myocardial contractile function (...
Cardiomyocyte injury occurs in myocardial ischemia, resulting in impairment of cardiac function. As the endogenous protective function of adult cardiomyocytes is limited, nonmyocytic cells may be activated to protect myocardium from ischemic injury. In this investigation, we demonstrated in a mouse model of myocardial ischemia that the liver was able to respond to myocardial ischemia to upregul...
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