نتایج جستجو برای: n arylidene 2 2 phenoxyphenyl acetohydrazide derivatives
تعداد نتایج: 3204168 فیلتر نتایج به سال:
A series of nine 2-arylidene-4-(4methoxy/phenoxy-phenyl)but-3-en-4-olides (I-IX) were screened against Pheretima posthuma earthworm species to assess the anthelmintic activity of the synthetic derivatives. The in vitro effects of compounds were evaluated at a concentration of 2mg/mL and time taken by the derivatives to paralyze and subsequently kill the worms was recorded. Synthetic butenolide ...
In the title compound, C9H12N2O, the dihedral angle between the benzene ring and the mean plane of the acetohydrazide group is 88.2 (7)°. In the crystal, N-H⋯O hydrogen bonds and weak C-H⋯O inter-actions link the mol-ecules into infinite ribbons along [001].
In the title compound, C(9)H(12)N(2)O(2), the acetohydrazide group is approximately planar [maximum deviation = 0.034 (2) Å]. In the crystal, mol-ecules are linked via inter-molecular N-H⋯O, N-H⋯N and C-H⋯O hydrogen bonds into infinite two-dimensional networks parallel to (001).
In the title compound, C(8)H(9)BrN(2)O, the 1-bromo-4-methyl-benzene group and the formic hydrazide moiety [r.m.s. deviations of 0.0129 and 0.0038 Å] are oriented at a dihedral angle of 80.66 (11)°. In the crystal, mol-ecules are linked via strong N-H⋯O hydrogen bonds, leading to the formation of chains in the [010] direction. These chains are linked via weaker N-H⋯N and N-H⋯O hydrogen bonds, w...
The title compound, C(10)H(15)N(3)O, crystallizes in an infinite two-dimensional polymeric network due to inter-molecular N-H⋯O hydrogen bonding. Intra-molecular N-H⋯N and inter-molecular C-H⋯N inter-actions are also present. The 3,4-dimethyl-phenyl unit is disordered over two sites with an occupancy ratio of 0.677 (5):0.323 (5). The dihedral angle between the benzene rings of the disordered co...
Fifty 2-[(arylidene)amino]-4,5-cycloalkyl[b]thiophene-3-carbonitrile derivatives were screened for their in vitro antifungal activities against Candida krusei and Cryptococcus neoformans. Based on experimentally determined minimum inhibitory concentration (MIC) values, we conducted computer-aided drug design studies [molecular modelling, chemometric tools (CPCA, PCA, PLS) and QSAR-3D] that enab...
In the title mol-ecule, C(9)H(13)N(3)O, the non-hydrogen atoms of the hydrazide group are essentially planar [maximum deviation = 0.028 (1) Å for one of the N atoms]. The mean plane of this group forms a dihedral angle of 83.34 (5)° with the plane of the benzene ring. In the crystal structure, mol-ecules are linked by inter-molecular N-H⋯O, N-H⋯N and weak C-H⋯N hydrogen bonds into a two-dimensi...
In the title compound, C(11)H(9)ClN(4)OS(2), the thia-diazole and chloro-phenyl rings are oriented at an angle of 43.1 (1)°. The sum of the bond angles around the amide N atom (359.8°) of the acetohydrazide group is in accordance with a model of sp(2) hybridization. In the crystal, inversion dimers linked by pairs of N-H⋯O hydrogen bonds generate R(2) (2)(8) loops. Weak C-H⋯π inter-actions also...
two novel 3-amino-5-(4-choloro-2-phenoxyphenyl)-4h-1,2,4-triazole derivatives were prepared and their anticonvulsant activity was measured by evaluation of the ability of these compounds to protect mice against convulsion induced by lethal doses of pentylenetetrazole (ptz). diazepam (sigma) was considered as a positive control drug with anticonvulsant effect [ed50 = 1.2 (0.5-1.9) mg/kg]. amongs...
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