Electrical measurements from large populations of animals would help reveal fundamental properties of the nervous system and neurological diseases. Small invertebrates are ideal for these large-scale studies; however, patch-clamp electrophysiology in microscopic animals typically requires invasive dissections and is low-throughput. To overcome these limitations, we present nano-SPEARs: suspende...

The effect of silicone nano-emulsion softener against silicone conventional emulsion softener on the physical properties of cotton fabric has been studied. It is observed that the nano-emulsion softener improves the feel, softness and crease recovery to a higher extent compared to the conventional emulsion softener. However, the nano form of emulsion causes higher loss in strength with increase...

Resistance to aspirin and its cytotoxicity significantly limits its therapeutic applications. Nano-liposomal encapsulation of aspirin can reduce its cytotoxicity. In this study, aspirin encapsulated nano-liposomes (AS-NL) was prepared and its performance in drug delivery and cytotoxicity was evaluated. The effects of two independent variables including: number of freeze/thawing cycles and conce...

Personalized treatment plans for cancer therapy have been at the forefront of oncology research for many years. With the advent of many novel nanoplatforms, this goal is closer to realization today than ever before. Inorganic nanoparticles hold immense potential in the field of nano-oncology, but have considerable toxicity concerns that have limited their translation to date. In this review, an...

By self-organization polymers form a large number of superstructures with characteristic dimensions in the range of a few nanometers up to several micrometers. They can be used to produce in a controlled way a wide range of nano-and microstructured materials such as nanoparticles, nanoporous materials and drug carriers. Applications in the fields of materials science, electronics, molecular bio...

Today’s, nanotechnology is integral part of pharmaceutics and Drug delivery system. In pharmaceutical science size is an important matter because it influences the drugs bioavailability; toxicity reduction; and better formulation. Nano size enhances drug performance many fold. It provides intelligent systems, devices and materials for better pharmaceutical applications. This review paper focuse...

In this review article, we describe the different nano-platforms developed in our laboratory at Northeastern University in Boston, MA for the targeted delivery of drugs and genes. Special emphasis is placed on nano-platforms that offer opportunities for multi-functionalization to allow for targeted stimuli-responsive and/or simultaneous strategic delivery of multiple drugs, genes, as well as th...

In part I of this review we assessed nanoscience-related definitions as applied to pharmaceuticals and we discussed all 43 currently approved drug formulations, which are widely publicized as nanopharmaceuticals or nanomedicines. In continuation, here we review the currently ongoing clinical trials within the broad field of nanomedicine. Confining the definition of nanopharmaceuticals to therap...