The realization of a high-throughput biosensor platform with ultrarapid detection of biomolecular interactions and an ultralow limit of detection in the femtomolar (fM) range or below has been retarded due to sluggish binding kinetics caused by the scarcity of probe molecules on the nanostructures and/or limited mass transport. Here, as a new method for the highly efficient capture of biomolecu...

This work has an innovative approach for the development of nanorobots with sensors for medicine. The nanorobots operate in a virtual environment comparing random, thermal and chemical control techniques. The nanorobot architecture model has nanobioelectronics as the basis for manufacturing integrated system devices with embedded nanobiosensors and actuators, which facilitates its application f...

BACKGROUND Detection of the human epididymis secretory protein 4 (HE4) biomarker plays an important role in the early diagnosis of ovarian cancer. This study aimed to develop a novel localized surface plasmon resonance (LSPR) biosensor for detecting HE4 in blood samples from patients with ovarian cancer. METHODS Silver nanoparticles were fabricated using a nanosphere lithography method. The a...

Nanooncology, the application of nanobiotechnology to the management of cancer, is currently the most important chapter of nanomedicine. Nanobiotechnology has refined and extended the limits of molecular diagnosis of cancer, for example, through the use of gold nanoparticles and quantum dots. Nanobiotechnology has also improved the discovery of cancer biomarkers, one such example being the sens...

Optical fiber sensors, thanks to their compactness, fast response and real-time measurements, have a large impact in the fields of life science research, drug discovery and medical diagnostics. In recent years, advances in nanotechnology have resulted in the development of nanotools, capable of entering the single cell, resulting in new nanobiosensors useful for the detection of biomolecules in...

In this study, we surface engineered living S. cerevisiae cells by decorating quantum dots (QDs) and traced the fate of QDs on molecular landscape of single mother cell through several generation times (progeny cells). The fate of QDs on cell-surface was tracked through the cellular division events using confocal microscopy and fluorescence emission profiles. The extent of cell-surface QDs dist...

The integration of biosensing platforms with drug delivery systems has led to effective treatment strategies for biomedical applications. With the emergency nanotechnology, manipulation materials in nanometer (nm) scale 1–100 ?nm, these and have been tremendously improved due exceptional properties exhibited by materials. conventional approaches used synthesize nanomaterials including physical ...

The space race is entering a new era of exploration, in which the number robotic and human missions to various places our solar system rapidly increasing. Despite recent advances propulsion life support technologies, there growing need perform analytical measurements laboratory experiments across diverse domains science, while keeping low payload requirements. In this context, lab-on-a-chip nan...

The optical measurement of single-walled carbon nanotubes (SWNTs) is a useful approach for understanding chirality characteristics because the excitation and emission wavelengths that produce maximum intensity are unique to SWNTs. properties SWNT in various biological applications envisaged be applicable nanobiosensors. Therefore, it necessary detect even small environmental changes, such as re...