The use of plasmon coupling in metal nanoparticles has shown great potential for the optical characterization of many biological processes. Recently, we have demonstrated the use of "plasmon rulers" to observe conformational changes of single biomolecules in vitro. Plasmon rulers provide robust signals without photobleaching or blinking. Here, we show the first application of plasmon rulers to ...

Discrete Au nanoparticle/DNA conjugates have been isolated by electrophoresis and used to form small groupings of particles, such as dimers and trimers. The use of purified conjugates leads to a higher yield of the target structure, and it has allowed us better control and understanding of the system. Newly accessible questions, such as the electrophoretic mobility of nanoparticle/DNA hybrids a...

This study describes the preparation, characterization, and controlled release of a streptomycin-chitosan-magnetic nanoparticle-based antibiotic in an effort to improve the treatment of bacterial infections. Specifically, chitosan-magnetic nanoparticles were synthesized by an incorporation method and were characterized by Fourier transform infrared spectroscopy, X-ray diffraction, thermogravime...

Over the last decade there has been significant progress in the synthesis of inorganic and hybrid inorganic-organic nanoparticles in solution. Optimizing the synthesis conditions is often dependent on structural characterization of the nanoparticles. Transmission Electron Microscopy (TEM) provides a method for structural characterization that provides both high-resolution details of individual ...

Organic nanoparticles of poly(styrene-co-maleimide) or SMI were synthesized in aqueous dispersion with a maximum concentration of 35 wt.% and are favorably applied in industrial coating processes. In order to evaluate the further processability and flow behavior of these nanoparticle dispersions, general rheological characterization under creep, oscillatory and rotational testing was done by ap...

The authors present a study of the optical and magneto-optical properties of Co nanoparticles embedded in two amorphous dielectric matrices with different refractive indices such as ZrO2 and Al2O3. The nanostructured films were prepared by pulsed laser deposition, and the morphology and structure were studied by different characterization techniques. The optical and magneto-optical MO propertie...

To control the severe problem of microbiologically influenced corrosion, industries require highly potent antibacterial agent which can inhibit the growth of bacteria on man-made surfaces. This need drove the research towards the synthesis of nanoscale antimicrobial compounds. We, therefore, screened several bacteria for the biosynthesis of copper/copper compound nanoparticles which could inhib...

The rapid growth in nanomaterial applications have revealed limitations in available physicochemical characterization methods. An in situ electrochemical small-angle neutron scattering (eSANS) methodology was devised that enables direct measurements of nanomaterial dispersion structure while undergoing reduction-oxidation (redox) reactions at the vitreous carbon electrode. Furthermore, these po...

Synthesis and characterization of magnetic nanoparticles with excellent size control are showed here. Their functionalization using an amphiphilic polymer is also described. This strategy allows the stabilization of magnetic nanoparticles in aqueous solvents and in addition, the polymer shell serves as a platform to incorporate relevant biomolecules, such as poly(ethylene glycol) and a number o...

Asymmetrical Flow Field-Flow Fractionation (AF4) is a separation technique applicable to particles over a wide size range. Despite the many advantages of AF4, its adoption in routine particle analysis is somewhat limited by the large footprint of currently available separation cartridges, extended analysis times and significant solvent consumption. To address these issues, we describe the fabri...