Lippia alba is a shrub found in all regions of Brazil and other countries in South and Central America. L. alba exhibits variability among its different accessions, showing differences in morphology and in the composition of its essential oil. This study evaluated the phenolic profiles and the antioxidant activities of seven different accessions of L. alba. The seven accessions of L. alba studi...

Background & objectives: Citrus lemon and lime juice, which contain high levels of vitamin C and natural antioxidant in the form of polyphenols, have a special place in the food basket of Iranian households. Flavonoids are among the polyphenolic compounds and Eriocitrin, Naringin and Hesperidin are among the most important flavonoids. Investigating the amount and type of polyphenols and flavono...

Flavanones constitute the majority of flavonoids in citrus fruits such as sweet (Citrus sinensis) and sour oranges (C. aurantium) and their near relatives—tangerines/mandarins (C. reticulata), tangors and tangelos. The relevant chemical analytic literature was searched, abstracted, documented, standardized, examined for quality, enumerated, and summarized in a database for these citrus flavanon...

Oxidative stress is one of the important causes of the type 1 diabetes induced changes in the sperm quality. Bioflavonoids, Rutin 10 mg/Kg and Naringin 10 mg/Kg were evaluated for their protective effects on sperm parameters, oxidative stress, and histopathology of type 1 diabetic rats. Results demonstrated the reduction in sperm count, sperm motility and vitality in diabetic rats. Mass drug ad...

The therapeutic effecicacy of a flavonoid Naringin (NG) against Cyclosporine A (CsA) induced nephrotoxicity was investigated in this study. Nephrotoxicity was induced in male albino wistar rats by injecting 25mg/kg body weight of CsA for a period of 21 days. CsA induced rats were also cotreated with 40mg of Naringin (NG/kg body weight) orally. After the experimental period the serum levels of u...

Objective Metals can cause male infertility through affection of spermatogenesis and sperm quality. Strong evidences confirm that male infertility in metal-exposed humans is mediated via various mechanisms such as production of reactive oxygen species (ROS). Flavonoids have antioxidant and metal chelating properties which make them suitable candidates for neutralizing adverse effects of metals ...

Fluoroquinolone antimicrobial drugs are absorbed efficiently after oral administration despite of their hydrophilic nature, implying an involvement of carrier-mediated transport in their membrane transport process. It has been that several fluoroquinolones are substrates of organic anion transporter polypeptides OATP1A2 expressed in human intestine derived Caco-2 cells. In the present study, to...