background and objective: according to the fact that neonatal infection is a challenging diagnosis field, several studies have tried to test sensitivity and specificity of diagnostic tests. this study was conducted to evaluate the sensitivity and specificity of procalcitonin (pct) as a single early marker of neonatal sepsis. materials and methods: in this study, 150 neonates admitted to nicu an...

septicemia in neonates is the commonest cause of mortality. early recognition and diagnosis of neonatal sepsis remains a challenge because of the variable and nonspecific clinical presentation. the laboratory criteria are often non specific and not fully reliable. the objective of this review is to highlight the various hematological and biological markers of neonatal sepsis. we searched pubmed...

Embryonic development time has been of long-standing interest to physiologists and ecologists because of its importance in understanding the behaviour and ecology of reproduction, and the evolution of reproductive strategies in animals. Yet, the relationship of embryonic development time to both neonate mass and incubation temperature remains poorly understood for most taxonomic groups. Here we...

Can people categorize the sex of neonate faces? Our experiment tested the sex categorization of neonate faces by adult participants. We used a set of 120 Caucasian faces (adults and 4-day-old neonates) that were presented just once to a large sample of participants. A computational model of low-level visual processing, based on Gabor filters, was used to explore the relation between spatial-fre...

In-utero transmission of rubella virus during pregnancy leads to congenital Rubella syndrome (CRS), which is characterized by cataracts, deafness and sensorineural hearing loss. While the nuclear cataract is the most frequently occurring abnormality, basal ganglia calcification is a rarer manifestation. The Risk of fetal transmission of rubella virus is highest during the first 12 weeks of gest...

OBJECTIVE We estimated the extent to which Canadian expectant parents would seek medical care in a febrile neonate (age 30 days or less). We also evaluated expectant parents' knowledge of signs and symptoms of fever in a neonate, and explored the actions Canadian expectant parents would take to optimize the health of their child. METHODS We conducted a cross-sectional survey of a sample of ex...

This study examines the functional implications of postnatal changes in the expression of the mitochondrial transporter protein, 2-oxoglutarate-malate carrier (OMC). Online (13)C nuclear magnetic resonance ((13)C NMR) measurements of isotope kinetics in hearts from neonate (3-4 days) and adult rabbits provided tricarboxylic acid cycle flux rates and flux rates through OMC. Neonate and adult hea...

Down syndrome (DS) is a genetic pathology characterized by intellectual disability and brain hypotrophy. Widespread neurogenesis impairment characterizes the fetal and neonatal DS brain, strongly suggesting that this defect may be a major determinant of mental retardation. Our goal was to establish, in a mouse model for DS, whether early pharmacotherapy improves neurogenesis and cognitive behav...

OBJECTIVE Several mechanisms of disease have been implicated in the pathophysiology of small-for-gestational-age (SGA) including an anti-angiogenic state, and an exaggerated intravascular pro-inflammatory response. Adiponectin plays a role in a wide range of biological activities including those that have been implicated in the pathophysiology SGA. Thus, the aim of this study was to determine i...

Contractile mechanisms of different parts of the gut in adult and neonate may not be identical due to developmental processes. The present study was undertaken to investigate acetylcholine (ACh) and histamine induced contractile responses of colon and rectum in adult and neonatal albino rats. Contractile responses were recorded from isolated in vitro preparations. The dose-response curve for AC...