نتایج جستجو برای: nephroprotective activity

تعداد نتایج: 1134807  

2015
Mohammed Jainuddin Yousuf Elangovan Vellaichamy

This study was designed to evaluate the protective activity of gallic acid (GA) against glyoxal (GO) an advanced glycation intermediate-induced renal fibrosis in experimental rats. Glyoxal (i.p) at a dose of 15 mg/Kg body weight/day for 4 weeks induces renal fibrosis. GA was administered orally (100 mg/Kg body weight/day) along with GO for 4 weeks. The anti-fibrotic activity of GA was analyzed ...

Journal: : 2022

All patients with chronic kidney disease (CKD) require treatment to reduce the risk of cardiovascular events and prevent progression renal failure. ACE inhibitors angiotensin receptor blockers are widely used for cardio- nephroprotection in CKD. Sodium glucose cotransporter type 2 (SGLT-2) show significant prospects reducing morbidity mortality this population. SGLT-2 have been developed diabet...

Journal: :GSC Biological and Pharmaceutical Sciences 2019

Journal: :Drug discoveries & therapeutics 2011
Y Fk Mahran A E Khalifa E El-Demerdash

Amino acids exert nephroprotective effects in various forms of acute renal injury depending on their renal hemodynamic effects. The present study was designed to elucidate and compare the role of non hemodynamic mechanisms in protective actions afforded by glycine and L-arginine against cisplatin (CDDP)-induced nephrotoxicity using rat renal cortical slices (RCS). We have investigated the possi...

2012
Mehdi Nematbakhsh Zahra Pezeshki Fatemeh Eshraghi-Jazi Farzaneh Ashrafi Hamid Nasri Ardeshir Talebi Tahereh Safari Maryam Haghighi Azam Mansouri

Background. The nephroprotective effect of vitamins E and C or losartan against cisplatin (CP)- induced nephrotoxicity when they are accompanied by estrogen was investigated. Methods. The ovariectomized rats received estradiol valerate for two weeks. At the end of the first week, a single dose of CP (7 mg/kg, IP) was also administered, and they received placebo (group 1), vitamin E (group 2), v...

Journal: :GSC biological and pharmaceutical sciences 2021

Background: Sea cucumbers have number of one a pharmacological effects counting anticancer, anticoagulant, anti-inflammatory, antioxidant, and wound healing. Biological properties therapeutic benefits can be connected to the presence wide cluster bioactive compounds particularly triterpene glycosides (saponins). Aims: The present study aimed explore hepatoprotective nephroprotective activity cu...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید