Objective: Cisplatin is potent chemotherapy for broad-spectrum malignancies treatment, but its use limited by organ toxicity effects, including nephrotoxicity. Glutamine prevents cisplatin nephrotoxicity inhibiting the oxidative stress in kidney cell apoptosis. Methods: This research examined nephroprotective effects of intravenous glutamine on glomerular epithelium male rats (Rattus norvegicus...

Lavandula stoechas is distributed in Africa, Europe, and Asia continents, especially the countries of Southern Europe North Africa neighboring Mediterranean. The use L. stoechas, which has a cosmopolitan distribution, mainly Mediterranean region, treatment rheumatic diseases reduction inflammatory problems folk medicine dates back to ancient times. It been determined that contains various bioac...

The aim of the study was to evaluate the nephroprotective and nephrocurative effects of Tephrosia purpurea (L.) Pers. leaves against gentamicin-induced acute renal injury in albino rats. The maximum free radical scavenging activity of the ethanolic extract was the basis for the selection of this extract for the in vivo study. Gentamicin (40 mg/kg, s.c.) was administered to induce toxicity in th...