Systemic lupus erythematosus (SLE) is a chronic, immunologic disorder that may affect multiple organ systems. Keratoconjunctivitis sicca is the most common ocular manifestation, but visual morbidity is usually due to retinal and neuro-ophthalmic manifestations of the disease. Ocular manifestations of lupus are a reflection of systemic disease. The presence of ocular manifestations should alert ...

Since 2011, use of immune checkpoint inhibitors (ICI) in cancer immunotherapy dramatically expanded, both alone and combination with either a different treatment or two ICIs. With this increase have come myriad adverse effects from enhanced activation, including ophthalmic neurologic related events (irAE). Neuro-ophthalmic (NOirAE) associated ICIs are increasingly recognized their severity may ...

abstract alzheimer’s disease (ad) is the most common cause of dementia in elderly people. the prevalence of alzheimer diseases is increasing in the world due to population aging. metabolic disease such as diabetes and obesity play important role in alzheimer disease. hyperglycemia can play important role in brain damage. it causes cognitive impairments, functional and structural alterations in ...

Two cases are described of hepatic fibropolycystic disease (Brunt, 1973). Both had neonatal pyloric stenosis, one craniostenosis and the other acromegaly and neuro-fibromatosis.