OBJECTIVE To study the role of diabetes, gynecomastia and CAG triplet repeat size as disease modifying factors of neurologic expression in spinal bulbar muscular atrophy (SBMA, Kennedy's disease). METHODS Twenty unrelated SBMA patients with confirmatory genetic testing were reviewed. Patterns of neurologic involvement were assessed (e.g. bulbar, asymmetric, proximal, distal, motor and sensory...

Paget's disease in the Far East is quite rare. Age at diagnosis is usually greater than 50 years, and the disease typically affects the spine. Most patients are usually diagnosed with Paget's disease following radiographic examination for other purposes. It usually occurs at multiple vertebral levels, with only 10-25% of vertebral Paget's disease being monostotic. The disease rarely causes neur...

abstract acute disseminated encephalomyelitis (adem) is a rare immune mediated and demyelinating disease of the central nervous system that usually affects children. it as a monophasic disorder related with multifocal neurologic symptoms. here in this paper we report seven cases of adem in pediatrics and besides a review of literatures are presented.

Neurologic disease in New World camelids (NWCs) is common, but the available literature regarding these diseases is fairly scarce given the relatively new introduction of camelids into the veterinary community. As NWC practice expands and more research is conducted to better understand these unique animals and their diseases, our ability to diagnose and treat neurologic conditions will likely i...

Serologic evidence suggests that West Nile virus (WNV) is widely distributed in horses in southern Africa. However, because few neurologic cases have been reported, endemic lineage 2 strains were postulated to be nonpathogenic in horses. Recent evidence suggests that highly neuroinvasive lineage 2 strains exist in humans and mice. To determine whether neurologic cases are being missed in South ...