Spinal and bulbar muscular atrophy (SBMA) is a motor neuron disease caused by the expansion of a polyglutamine tract within the androgen receptor. This disease is unusual among the polyglutamine diseases in that it involves lower motor and sensory neurons, with relative sparing of other brain structures. We describe the development of transgenic mice, created with a truncated, highly expanded a...

Functional neurological disorder (FND) may mimic various kinds of neurologic diseases and coexist with other disorders. In cases overlapped by FND, it might be challenging to distinguish symptoms induced FND those underlying disorders, especially when patients show no positive signs indicative FND. Here, we present the case a patient who was genetically diagnosed paroxysmal kinesigenic dyskines...

Present report describes a 46 year old male patient with a diagnosis of major depression who developed tardive dyskinesia during bupropion therapy. Our patient had no history of neuroleptic use and his laboratory and neurologic examinations were normal. He had no family history of neurologic diseases. Although bupropion induced dyskinesia has been previously reported in the literature, it is ra...

Functional disorders are one of the most common diagnoses in neurologic practice, but this is not reflected in current classification systems. The 11th revision of the World Health Organization's International Classification of Diseases (ICD-11) in 2017 offers an opportunity for these disorders to appear within both neurologic and psychiatric categories for the first time. We discuss the ration...

Objective This study was conducted to determine psychiatric diseases accompanying common neurological diseases. Material and Methods The is a retrospective study. files of 1125 patients diagnosed with neurologic disease who were treated as an outpatient in the psychiatry clinic between 26.12.2016 - 26.12.2017 examined. Results most commonly depression 59.9% anxiety disorder 42.5% neurology rece...

the human brain is composed of several interconnected, functionally distinct structures and much debate has surrounded the basic question of how these structures evolve. brain development begins in early gestation. between 4 weeks and 9 months, brain undergoes rapid development. there are six stages of nervous system development. brain increases connections between birth and 21 years of age. ab...