Objectives To describe the clinical, neurophysiological and histopathological profile of patients with leprosy neuropathy neuropathic pain from a referral service for in southeastern Brazil. Results Among data analyzed, we found statistically significant correlation between duration associated pain, also age patient number nerves affected nerve conduction studies. We inverse relationship score ...

abnormalities of blinking in childhood are not uncommon. to determine the characteristics and causes of excessive blinking, this prospective, non–comparative consecutive case series study was carried out. in outpatient clinics of ophthalmology and neurology of our hospital, 60 children aging 2-16 years old with excessive blinking were examined. detailed ophthalmologic and neurologic evaluation ...

PURPOSE Pharmacovigilance Research Network built a spontaneous reporting system and collected adverse drug reactions (ADRs) by electronic submission (e-sub) in Korea. We analyzed ADRs spontaneously reported through e-sub from regional health professionals. MATERIALS AND METHODS Nine hundred and thirty three ADR cases were collected and analyzed from January to December in 2008. "A matter" was...

Human T-cell lymphotropic virus (HTLV) types 1 and 2 belong to the Oncorna group of retroviridae, a large family of viruses, grouped initially by pathogenic features, but later revised on the basis of genome structure and nucleotide sequence. HTLV-I was the first discovered human retrovirus to be associated with a malignancy in 1980. The malignancy, first described by Uchiyama and co-workers in...

PURPOSE Hand-foot-mouth disease (HFMD) is a common viral illness in children, which is usually mild and self-limiting. However, in recent epidemics of HFMD in Asia, enterovirus 71 (EV71) has been recognized as a causative agent with severe neurological symptoms with or without cardiopulmonary involvement. HFMD was epidemic in Korea in the spring of 2009. Severe cases with complications includin...

In addition to their well characterized role in allergic inflammation, recent data confirm that mast cells play a more extensive role in a variety of immune responses. However, their contribution to autoimmune and neurologic disease processes has not been investigated. Experimental allergic encephalomyelitis (EAE) and its human disease counterpart, multiple sclerosis, are considered to be CD4(+...

RATIONALE Marchiafava-Bignami disease (MBD) is a rare disease characterized by demyelination of the corpus callosum. It is most commonly seen in patients with chronic alcoholism. The clinical diagnosis of MBD can be difficult due to its nonspecific manifestation. Central pontine myelinolysis (CPM) occurs mostly as a complication of severe and prolonged hyponatremia, especially when corrected to...

Lyme disease is an infectious disease transmitted by ticks, and distributed in North America and across a wide area of Eurasia. It is considered one of the major emerging diseases from a public health perspective. An outbreak of Lyme disease was first reported in the United States in the 1970s. The presence of Borrelia burgdorferi, its causative organism, in the skin results in the development ...

Neurolymphomatosis is an extremely rare neurologic manifestation of systemic lymphoma in which B-cell nonHodgkin’s lymphoma a much more common cause. Neurolymphomatosis must be differentiated from more frequent neurologic manifestations of lymphoma, including peripheral nerves compression by enlarged lymph nodes, radiation plexopathy, herpes zoster infection, and lymphoma-associated vasculitis....

BACKGROUND Choreoacanthocytosis (CHAC) (Online Mendelian Inheritance in Man accession No. 200150) is a hereditary neurodegenerative syndrome characterized by movement disorders, cognitive decline, myopathy, behavioral changes, and acanthocytosis and is caused by mutations in the VPS13A gene. OBJECTIVE To describe the cases of 2 Mexican women with clinical and molecular characteristics compati...