Neuropathic pain is defined by International Association for Study of Pain (IASP) as pain arising as a direct consequence of lesion or disease of the system either somatosensory system either at peripheral or central level [1]. Diabetic neuropathy and Postherpetic neuralgia are major causes of neuropathic pain. It has been seen that neuropathy is a common complication of diabetes, affecting up ...

The incidence and type of neuropathy in patients with chronic obstructive pulmonary disease (COPD) were assessed. In a selected group of 89 patients, abnormal nerve conduction studies were found in 44%. Electrophysiological signs of a generalized peripheral neuropathy were found in 5-18%, depending on diagnostic criteria. Lesions which were thought to be due to compression or other forms of tra...

OBJECTIVE Neurological complications of celiac disease (CD) include neuropathy, myeloneuropathy, and cerebellar degeneration. The cause of neuropathy in patients with CD is not known. Prior publications describe copper deficiency in CD patients with myeloneuropathy and neuropathy and posit that hypocupremia is the cause of these neurological conditions. However, based on our clinical experience...

This study assessed whether painful diabetic neuropathy is associated with abnormal sympathetic nervous function in the affected limbs. Nine patients with diabetes (four men, five women; age 61 +/- 7 years) and painful peripheral neuropathy of the feet, but without evidence of generalized autonomic neuropathy, underwent intravenous infusion of tritiated norepinephrine (NE) and sampling of arter...

OBJECTIVES To estimate neuropathic sign/symptom rates with initiation of combination antiretroviral therapy (cART) in HIV-infected ART-naive patients, and to investigate risk factors for: peripheral neuropathy and symptomatic peripheral neuropathy (SPN), recovery from peripheral neuropathy/SPN after neurotoxic ART (nART) discontinuation, and the absence of peripheral neuropathy/SPN while on nAR...

Introduction: Mirogabalin is a new drug from the gabapentinoid group first registered in Japan 2019. It has found use treatment of peripheral neuropathic pain diabetic neuropathy and postherpetic neuropathy. Purpose: In this article, we review studies on efficacy safety mirogabalin indications its potentially applications. Materials Methods: We reviewed literature available PubMed database, usi...

We commend Gemignani and colleagues for important observations 1 on the prevalence of Restless Legs Syndrome (RLS) in 104 patients with symptoms of exclusive small fiber neuropa-thy, peripheral neuropathy, or mononeuropathy multiplex. The co-occurrence of neuropathy and RLS has been studied from two standpoints in the past, without reaching a consensus: the frequency of neuropathy in RLS patien...

A family with neuralgic amyotrophy (idiopathic brachial plexus neuropathy) associated with a multifocal sensory neuropathy is described. Four members over two generations were affected by neuralgic amyotrophy, inherited as an apparent autosomal dominant trait; two also had a multifocal relapsing sensory neuropathy with the clinical features of Wartenberg's migrant neuropathy.

Dear Editor: We read with great interest, the case report on ischemic optic neuropathy (1). We would like to add a few points concerning the blood supply of the optic nerve and the correlation with the development of post-operative ischemic neuropathy. Actually, the perioperative or post-operative vision loss (postoperative ischemic neuropathy) is most likely due to ischemic optic neuropathy. I...

This study was conducted to investigate the toxicity and efficacy of modified FOLFOX6 plus bevacizumab in patients with metastatic colorectal cancer with particular regard to oxaliplatin-induced neuropathy. Toxicity was graded according to the National Cancer Institute Common Terminology Criteria for Adverse Events (NCI-CTCAE) (version 3.0). The evaluation was especially focused on grade 2 oxal...