background: although cervical cancer mortality has reduced during last years, but it is still leading cause of mortality among women. many efforts have performed to develop new drugs and strategy to cure cervical cancer. mesenchymal stem cells (mscs) have many advantages that make them a suitable choice as a cell therapeutic agent in cancer treatment. there are different transfection methods fo...

The application of chemotherapy in cancer treatment has been limited due to cause side effects such as toxicity against normal cells and drug resistance. In recent years, numerous studies have been focused on using natural products with chemotherapeutic drugs to enhance therapeutic efficiency and reduce cytotoxicity. On the other hand, encapsulation of drugs into nanoparticles (NPs) can improve...

If a new drug is supposed to replace existing pharmaceuticals we subtracted costs of replaced drugs [table 2]. If a new drug is supposed to be given additionally, we added costs of new drugs. For calculations, we assumed that newly launched drugs will reach on average a diffusion of 20% of their market potential until 2016. Market potential was defined as for a new drug eligible patients. To as...

I assess the impact that pharmaceutical innovation had on cancer mortality in Mexico during the period 2003–2013, by investigating whether there were larger declines in the age-standardized mortality rate of cancer sites (breast, lung, colon, etc.) that were subject to more pharmaceutical innovation, controlling for changes in the age-standardized cancer incidence rate. The estimates indicate t...

BackgroundHigh treatment prices of new cancer drugs are a global public health challenge to patients and healthcare systems. Policymakers in the US Europe debating reforms drug pricing. The objective this study was assess whether efficacy or epidemiological characteristics (prevalence, incidence, mortality) explain gap between non-cancer US, Germany, Switzerland.MethodsThis cross-sectional iden...