Newcastle disease (ND) is a highly contagious, severe disease of poultry caused by pathogenic strains of Newcastle disease virus (NDV; or avian paramyxovirus-1). NDV is endemic in wild birds worldwide and one of the economically most important poultry pathogens. Most of the published strains are outbreak-associated strains, while the apathogenic NDV strains that occur in wild birds, posing a co...

Strains of Newcastle disease virus (NDV) can be separated into genotypes based on genome differences even though they are antigenically considered to be of a single serotype. It is widely recognized that an efficacious Newcastle disease (ND) vaccine made with any NDV does induce protection against morbidity and mortality from a virulent NDV challenge. However, those ND vaccines do not protect v...

In this study, we report the complete genome sequence of a novel Newcastle disease virus (NDV) strain, Sheldrake duck/China/Guizhou/SS1/2014, isolated from Sansui Sheldrake duck flocks in Guizhou Province, southwestern China. The genome of this isolate is 15,192 nucleotides in length, which belongs to NDV genotype VIId in class II. This discovery will help us further study the epidemiology char...

Circulating interferon production, induced by Newcastle disease virus, is about seven times higher in C57 Black mice than in Balb/c/Gif mice. A Mendelian analysis was carried out and circulating interferon production was measured in reciprocal F1 hybrids, in the F2 generation, in progeny of backcrosses of F1 hybrids to either parent strain, and in second backcross progeny. The results indicate ...

On June 2005, a respiratory disease was observed in the chickens of a large broiler farm in Kermanshahprovince, west of Iran. Relatively severe respiratory signs started with sneezing at 27 days of age. Thedisease lasted up to the end of fattening period and accompanied by increased mortality (13.6%). At postmortemexamination, tracheitis, airsacculitis and pneumonia were obvious. Serologic exam...

The use of different types of Newcastle disease (ND) vaccine in different vaccination schemes has decreased the incidence of velogenic Newcastle disease (VND) in commercial poultry worldwide. In under-developed countries like Pakistan, these vaccination schemes are not successful due to free-range and backyard poultry production. This trial was conducted in 90 experimental chickens to develop a...