Extracts of a fluorescent species of Pseudomonas grown with m-cresol, degrade gentisic acid without isomerization of the ring-fission compound, maleylpyruvate, to give eventually d-malate and pyruvate. d-Malate is also a growth substrate. l-Malate but not d-malate is oxidized by a particulate enzyme not requiring nicotinamide adenine dinucleotide (NAD) or nicotinamide adenine dinucleotide phosp...

Abstract Tropical xero-epiphytic orchids undergo a photosynthetic mechanism called ‘Crassulacean Acid Metabolism’, modification of Calvin–Benson cycle. This anabolic process aids in the long-term retention organically fixed CO 2 , imprinting them as active sequestrators and fixers gaseous . The malate decarboxylation competence enzymes—phosphoenolpyruvate carboxykinase (PEPCK), Nicotinamide Ade...

Background and Purpose: Chronic granulomatous disease (CGD) is an inherited disorder of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex. This disorder results in recurrent life-threatening bacterial and fungal infections. Aspergillus species are the most common fungal infections in these patients. Case Report: Herein, we present a case of fungal infection in a girl wi...

Submit Manuscript | http://medcraveonline.com Abbreviations: AGEs: Advanced Glycation End-products; ROS: Reactive Oxygen Species; DM: Diabetes Mellitus; RAGE: Receptors of AGEs; HLA: Human Leucocyte Antigen; GDM: Gestational Diabetes Mellitus; MODY: Maturity Onset Diabetes of the Young; SMBG: Self Monitoring Blood Glucose; HAS: Human Serum Albumin; HMA: Human Mercaptalbumin; PCO: Protein Carbon...

Molybdenum is absolutely required for the nitrate-reducing activity of the nicotinamide adenine dinucleotide nitrate reductase complex isolated from Chlorella fusca. The whole enzyme nicotinamide adenine dinucleotide nitrate reductase is formed by cells grown in the absence of added molybdate, but only its first activity (nicotinamide adenine dinucleotide diaphorase) is functional. The second a...

Niacin, also known as vitamin B3, is required for the synthesis of coenzymes, nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). Niacin binds with G protein-coupled receptor (GPR) 109A on cutaneous Langerhans cells and causes vasodilation with flushing in head and neck area. Niacin deficiency due to excessive alcohol consumption, certain drugs or ina...

I t was shown by Collier and Pappenheimer (1) that inhibition, by diphtheria toxin, of amino acid incorporation into polypeptides in cell-free systems isolated from mammalian cells requires the presence of nicotinamide adenine dinucleotide (NAD) as an essential cofaetor. In the absence of NAD, there is no inhibition of amino acid incorporation, even in the presence of high toxin concentrations....

Horikoshi, Koki (The Institute of Physical and Chemical Research, Tokyo, Japan), Shigeji Iida, and Yonosuke Ikeda. Mannitol and mannitol dehydrogenases in conidia of Aspergillus oryzae. J. Bacteriol. 89:326-330. 1965.-A sugar alcohol was isolated from the conidia of Aspergillus oryzae and identified as d-mannitol. Two types of d-mannitol dehydrogenases, nicotinamide adenine dinucleotide phospha...

The effects of 5-azacytidine (5-AC) administration on the he patic cytochrome P-450 systems of mice were studied. A single i.p. dose of 5-AC (25 mg/kg) to male Swiss-Webster mice caused about a 50% depression of microsomal cytochromes P-450 and os and of ethylmorphine W-demethylase and ethoxycoumarin Odeethylase activities. Depression was greatest 24 h after treat ment; by 48 to 72 h, cytochrom...