Abstract INTRODUCTION Treatment of brainstem tumors is often initiated without a tissue diagnosis due to the risk biopsy. A subset gliomas harbor an isocitrate dehydrogenase 1/2 (IDH) mutation, which predicts response alkylator chemotherapy and IDH inhibitors; non-invasive diagnostic tests are needed identify these mutations. METHODS We identified cohort patients with IDH-mutant through chart r...

invasive aspergillosis is one of the leading causes of morbidity and mortality among solid organ transplant recipients, especially in lung transplantations. diagnosis of invasive aspergillosis is one of the current challenges due to nonspecific clinical symptoms and broad differential diagnosis. definitive diagnosis usually requires invasive procedures, including bronchoscopy and ctguided biopsy