نتایج جستجو برای: noninvasive prenatal screening nips

تعداد نتایج: 293051  

جلالی, حسین, خوش آئین, عاطفه, مهدوی, محمدرضا, کوثریان, مهرنوش, روشن, پیام ,

 Background: Beta thalassemia is one of the most common hereditary disorders worldwide. In Iran, it is frequently reported from northern and southern provinces. In order to prevent child birth affected by this complication, prenatal screening and diagnosis is carried out nationwide. However in some instances, this program is unable to identify rare mutations leading to thalassemia. Case ...

Journal: :Ultrasound in Obstetrics and Gynecology 1995

Journal: :Health technology assessment 2003
F J Song P Barton V Sleightholme G L Yao A Fry-Smith

OBJECTIVES To compare the effectiveness, estimate the associated costs, and summarise available evidence about the feasibility and acceptability of different screening strategies in England and Wales. Also to establish a model for estimating effectiveness and costs of these different strategies. DATA SOURCES Literature searches were restricted to MEDLINE and EMBASE, as well as citations in in...

Journal: :Journal of the Royal Society of Medicine 1996

Journal: :International journal of laboratory hematology 2013
C C Hoppe

The hemoglobinopathies encompass a heterogeneous group of disorders associated with mutations in both the alpha-globin and beta-globin genes. Increased immigration of high-risk populations has prompted the implementation of prenatal and newborn screening programs for hemoglobinopathies across Europe and North America. In Canada, the UK, and other European countries, prenatal screening to identi...

Journal: :Obstetrical & gynecological survey 2011
Lauren C Sayres Mildred K Cho

UNLABELLED Cell-free fetal nucleic acids circulating in the blood of pregnant women afford the opportunity for early, noninvasive prenatal genetic testing. The predominance of admixed maternal genetic material in circulation demands innovative means for identification and analysis of cell-free fetal DNA and RNA. Techniques using polymerase chain reaction, mass spectrometry, and sequencing have ...

Journal: :The New England journal of medicine 2014
Diana W Bianchi R Lamar Parker Jeffrey Wentworth Rajeevi Madankumar Craig Saffer Anita F Das Joseph A Craig Darya I Chudova Patricia L Devers Keith W Jones Kelly Oliver Richard P Rava Amy J Sehnert

BACKGROUND In high-risk pregnant women, noninvasive prenatal testing with the use of massively parallel sequencing of maternal plasma cell-free DNA (cfDNA testing) accurately detects fetal autosomal aneuploidy. Its performance in low-risk women is unclear. METHODS At 21 centers in the United States, we collected blood samples from women with singleton pregnancies who were undergoing standard ...

Journal: :Journal of pediatric hematology/oncology 2012
Barakat Adeola Animasahun Urowoli Nwodo Olisamedu Fidelis Njokanma

Nigeria has the highest population of sickle cell anemia (SCA) patients in the whole world. This condition manifests with frequent episodes of aches and pains, recurrent infections, and frequent hospitalization. Prenatal screening is one of the methods of reducing the prevalence of this disease. The study aimed to determine the awareness and acceptability of prenatal screening for SCA among hea...

2014
Victor Heorhiadi Seyed Kaveh Fayaz Michael K. Reiter Vyas Sekar

Growing traffic volumes and the increasing complexity of attacks pose a constant scaling challenge for network intrusion prevention systems (NIPS). In this respect, offloading NIPS processing to compute clusters offers an immediately deployable alternative to expensive hardware upgrades. In practice, however, NIPS offloading is challenging on three fronts in contrast to passive network security...

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