The present study was aimed at elucidating the protective effect of ferulic acid (FA), a natural polyphenol against nicotine-induced tissue damage, including lung, liver and kidney of experimental rats. Female albino rats of Wistar stain were used for the experimental study. Lung toxicity was induced by subcutaneous injection of nicotine at a dose of 2.5 mg/kg body weight (5 days a week, for 22...

the introduction of ex vivo lung perfusion (evlp) in the practice of lung transplantation has allowed the reconditioning of the marginal grafts and their conversion into transplantable grafts. in addition, evlp can provide a platform for the application of various preventive measures to decrease the incidence of post-transplant complications. while the toronto team targets the attenuation of th...

The left pulmonary artery and ductus arteriosus were ligated in 14 pigs at birth. Animals were killed at intervals between two and 24 weeks of age. In all animals, serial chest radiographs were taken. In eight animals, nitrogen-13 lung function studies showed normal fractional ventilation in both lungs and continued growth of the small left lung. After death, the fixed inflated volume was deter...

Quantitative studies have, for the first time, been carried out on the single lung in a case of unilateral pulmonary aplasia, in which the other lung was represented by a rudimentary bronchial stump. The patient died at the age of 3 months. The lung was enlarged to almost twice the normal volume, filling the intrathoracic cavity. The bronchial generations were reduced in number. Pulmonary arter...

We report a rare case of dual arterial supply to an otherwise normal lung discovered incidentally during initial angiography performed with the intent of chemoembolization of hepatocellular carcinoma. In addition to normal hepatic arterial supply, the proper hepatic artery provided systemic arterial supply to the lower lobe of the left lung. Subsequent chest computed tomography angiography demo...

We hypothesized that exposure to hypergravity in the supine and prone postures causes a redistribution of pulmonary blood flow to dependent lung regions. Four normal subjects were exposed to hypergravity by use of a human centrifuge. Regional lung perfusion was estimated by single-photon-emission computed tomography (SPECT) after administration of (99m)Tc-labeled albumin macroaggregates during ...

P120-catenin plays an important role in cell adhesion and signalling transduction though the function of its isoforms is unclear. The aim of this study was to examine the expression of p120-catenin isoforms in lung cancer and investigate their relationship to clinicopathological factors in lung squamous cell carcinomas (SCCs) and adenocarcinomas. The expression patterns of p120-catenin in lung ...

a 55 year-old man was referred with periumbilical and colicky abdominal painøœ cutaneous lesionsøœ palpable purpura in extremities and 10 kg weight loss. a 5×5 cm cavitary mass lesion was seen in the lower lobe of right lung in cxr. pansinusitis in paranasal ct scan was reported. intramural hemorrhage in ileum and jejunum in abdominal ct scan was noted. esr was ›100 and c-ancawas positive.micro...

O UT OF THE SEVERAL REPORTED EXperiments of lung reimplantation, a few basic concepts have been derived. A number of dogs have survived for long periods of time after reimplantation of one lung; however, the animals do not live for more than a few weeks after complete one stage removal of the contralateral normal lung.”#{176} The ventilatory function and oxygen consumption value of the transpla...