Background: Surface roughness is one of the most important characteristics endodontic instruments, correlating to instrument fracture. The purpose this study was measure surface values these instruments before and after resin root canal preparation without previous glide path preparation, with new method. Data obtained from field emission scanning electron microscope...

Background: Exercise has been identified as an allied health strategy that can support the management of depression in older adults, yet relative effectiveness for different exercise modalities is unknown. To meet this gap knowledge, we present a systematic review and network meta-analysis randomised controlled trials (RCTs) to examine head-to-head aerobic, resistanc...

Background: Use of telephone, video and e-consultations is increasing. These can make consultations more transactional, potentially missing patients’ concerns. This study aimed to develop a complex intervention address concerns comprehensively in general practice test the feasibility this cluster-randomised framework. The used two technologies:<ns3:bol...

Background COVID-19 continues to pose a significant risk human health and is prominent global vampire. diseases have similar burden in all parts of the world, but they present challenge public low- middle-income nations like Bangladesh. The primary purposes study are describe extent which has increased cost living for average Bangladeshi identify chron...

BACKGROUND Although the development of novel therapeutic regimens to combat hepatitis C virus (HCV) infection have been speeded up with successful results, no efficient vaccines exist yet. OBJECTIVES This study aimed to construct a eukaryotic expression vector encoding nonstructural proteins, NS3/NS4A, of HCV genotype 3a, and evaluate its expression on Huh7 cell surface. MATERIALS AND METHO...

The segment 10 (S10) genes of African horsesickness virus (AHSV), Palyam virus and epizootic haemorrhagic disease virus were translated in vitro in a rabbit reticulocyte lysate system. Each of the S10 genes encoded two proteins NS3 and NS3A, which were shown to be related by peptide mapping. Cloned copies of the S10 genes of two AHSV serotypes (AHSV-3 and AHSV-9) and Palyam virus were sequenced...

The HCV genome encodes, within the NS3 gene, a serine protease whose activity specifically cleaves the viral polyprotein precursor. Proteolytic processing of HCV polyprotein precursor by the viral NS3 proteinase is essential for virion maturation and designing specific inhibitors of this protease as possible anti-viral agents is a desirable and practical objective. With a view to studying both ...

IIntroduction : Bronchiolitis is the leading cause of hospitalization in children. Estimate potentially preventable variables that impact length hospital stay are a priority to reduce costs associated with this disease. This study aims identify clinical bronchiolitis children tropical middle-income country Methods:</ns3:b...

Hepatitis C viruses (HCV) encode a helicase enzyme that is essential for viral replication and assembly (nonstructural protein 3 [NS3]). This helicase has become the focus of extensive basic research on the general helicase mechanism, and it is also of interest as a novel drug target. Despite the importance of this protein, mechanistic work on NS3 has been conducted almost exclusively on varian...

Background: Previous research has consistently shown the significant difference in outcome between cancerous and non-cancerous patients with coronavirus disease 2019 (COVID-19). However, no studies have compared clinical manifestation of COVID-19 hematologic cancers solid patients. Therefore, we analyzed hematological cancer primary worldwide through a meta-analysis ...