Osteoarthritis (OA), the most common form of joint disease in the elderly, is a progressive destructive process characterized by metabolic and structural changes in the cartilage, bone and articular surfaces. The management of OA involves both non-pharmacologic and pharmacologic approaches of therapy. Such modes of therapy may prove ineffective in some patients and moreover, have been found to ...

The oral bioavailability of many lipophilic bioactive agents (pharmaceuticals and nutraceuticals) is limited due to various physicochemical and physiological processes: poor release from food or drug matrices; low solubility in gastrointestinal fluids; metabolism or chemical transformation within the gastrointestinal tract; low epithelium cell permeability. The bioavailability of these agents c...

Noncommunicable chronic diseases such as inflammatory bowel diseases, cancer, diabetes, obesity, and pulmonary, cardiovascular, and neurodegenerative diseases are becoming the leading cause of death throughout the world. Unhealthy diet, smoking, lack of exercise, stress, radiation exposure, and environmental pollution are among the common causes of chronic diseases. Most of these risk factors a...