Chronic uraemia is associated with severe disturbances in the calcium, phosphorus and vitamin D homeostasis, leading to the development of secondary hyperparathyroidism (HPT) with increased biosynthesis and secretion of parathyroid hormone (PTH) and hyperplasia of the parathyroid glands. Renal osteodystrophy (ROD) is a frequent and serious complication in chronic uraemic patients, which in a ma...

In our first 200 cases of primary hyperparathyroidism confirmed by operation 12 were also shown to have a long history either of a malabsorption syndrome or of chronic renal-glomerular failure. We consider that they first went through a phase of secondary hyperparathyroidism, during which one or more of the glands became autonomous adenamata. This then produced the biochemical changes of "prima...

We present the case of a 57-year old man who underwent total parathyroidectomy with autotransplantation into the brachioradial muscle (Wells' method) due to secondary hyperparathyroidism as a complication of chronic renal failure. Three years later the patient developed recurrent secondary hyperparathyroidism due to graft hyperplasia resulting in the removal of the graft. We point out various p...

INTRODUCTION Brown tumors are a rare focal manifestation of osteitis fibrosa cystica, which results from hyperparathyroidism. Chronic kidney failure may lead to secondary or tertiary hyperparathyroidism and thus to osteitis fibrosa cystica and brown tumors. CASE PRESENTATION A 60-year-old man with a history of diabetes mellitus and chronic kidney failure presented with a 15-day history of dys...