PURPOSE To evaluate the relationship between the displacement of the lamina cribrosa (LC) and prelaminar tissue with corneal hysteresis (CH) using spectral-domain coherence tomography (SD-OCT) after reducing intraocular pressure (IOP) with medical treatment. METHODS Sixty-one eyes of 61 patients with ocular hypertension or primary open-angle glaucoma who were going to start with treatment wer...

UNLABELLED Studying biomechanical properties of the fibrous tunic of the eye meets current clinical demands. Previous studies have proved bidirectional corneal applanation suitable for this purpose. The so called corneal elasticity coefficient is more informative in terms of corneal elastance than the two other parameters measured during bidirectional corneal applanation, namely, corneal resist...

PURPOSE The Ocular Response Analyzer (ORA) proposes to measure corneal biomechanical properties in vivo by monitoring and analyzing the corneal behavior when this structure is submitted to a force induced by an air jet. The purpose of this study was to evaluate the relationship between corneal biomechanical properties and corneal-compensated intraocular pressure (IOPCC) measurements as obtained...

BACKGROUND The aim of this study was to determine the correlation between corneal hysteresis (CH) and the corneal resistance factor (CRF), which are both novel methods of analyzing ocular rigidity/elasticity, and various corneal characteristics, mainly corneal volume in normal subjects. METHODS This cross-sectional study included 500 normal eyes of volunteers. An ocular response analyzer (ORA...

Glaucoma is one of the most dreadful ocular conditions that affects millions of people worldwide and is one of the major causes of irreversible blindness. Although glaucoma is a complex and poorly understood disorder, the primary goal of therapy is lowering Intraocular Pressure (IOP), which is not only one of the most significant risk factors in development of the disease, but also the only mod...

It is important for almost all transaction processing and computer-communication systems to satisfy response time quantile targets. This paper describes HYDRA, a scalable parallel tool for the analytical determination of response time densities in large, structurally-unrestricted Markov models derived from high-level specifications. The tool exploits an efficient distributed uniformization-base...

To evaluate corneal hysteresis (CH), acquired with ocular response analyzer (ORA), as a risk factor for glaucoma progression in early-stage primary open-angle (POAG). In historical cohort study, patients diagnosed 2011 POAG according to the Hodapp, Parrish and Anderson classification modified Octopus perimetry followed up until glaucomatous development; otherwise, observations were censored Oct...

OBJECTIVE To determine clinical value of the use of the upper limit of individual normal range of intraocular pressure (IOP) in glaucoma diagnosing. MATERIAL AND METHODS The study enrolled 229 conditionally healthy participants (229 eyes) with no ocular complaints after a basic ophthalmic assessment. Ocular blood flow and IOP were measured with Ocular Blood Flow Analyzer (Paradigm Medical Ind...

AIM To investigate the accuracy of intraocular pressure (IOP) as measured by a Reichert Ocular Response Analyzer (ORA), as well as the relationship between central corneal thickness (CCT) and IOP as measured by ORA, Goldmann applanation tonometry (GAT), and dynamic contour tonometry (DCT). METHODS A total of 158 healthy individuals (296 eyes) were chosen randomly for measurement of IOP. After...

Chronic smoking has negative effects on the ocular surface; chronic smokers had lower Schirmer scores in the corneas [1], a higher degree of squamous metaplasia [2,3], a higher grade of lipid layer changes in tears [3], and lower tear film break-up time compared with non-smokers [1-4]. Smoking also affects tear secretion and protein components in tears [5,6]. Furthermore, cigarette smoking may ...