Subjects, methods, and results I assessed 22 infants and children with fractures (mean age 6 months) who were the subjects of proceedings for child protection (19) or whose parents had been charged with causing their injuries (three). I scrutinised the medical notes, court papers, and x ray films for evidence of metabolic bone disease, particularly osteogenesis imperfecta (using the classificat...

OBJECTIVES The purpose of this study was to use quantitative x-ray microprobe analysis with scanning electron microscopy to define the morphostructural and calcification patterns in the enamel of teeth with the hypomineralized variant of amelogenesis imperfecta. STUDY DESIGN We compared 5 fragments of permanent human canines from patients with clinically diagnosed hypomineralized amelogenesis...

BACKGROUND AND OBJECTIVES Osteogenesis Imperfecta is an uncommon genetic connective tissue disease with prevalence of 1/10000, primarily involving endochondral ossification, resulting in brittle bones, multiple fractures and skeletal deformities. This article aimed at reporting a case of Osteogenesis Imperfecta patient submitted to total intravenous anesthesia for fractured femur surgical repai...

The purpose of our study was to screen preliminary differential expression bone-related microRNAs (miRNAs) in serum of patients with osteogenesis imperfacta and to clarify whether serum microRNA is a promising biomarker for osteogenesis imperfecta. geNorm and several other programes were performed to select suitable reference genes for quantitative detection of serum miRNAs from 6 candidate con...

Odontogenesis occurs because of a multi-stage complicated interaction between the oral epithelium and the mesenchymal tissue under the epithelium. Abnormal tissue interactions during this process can lead to ectopic tooth development (1). Ectopic tooth outside the oral cavity is rarely reported in the literature (1, 2) Ectopic teeth can be asymptomatic or can form odontogenic cysts, cause degra...