Central odontogenic fi broma (COF) is a rare benign odontogenic tumor characterized by variable amounts of inactive-looking odontogenic epithelium embedded in a mature fi brous stroma corresponding to 0-5.5% of all odontogenic tumors. COF may be seen at any age, but it is diagnosed most frequently in patients between the second and fourth decades of life. The lesion is asymptomatic except the s...
