نتایج جستجو برای: oesophageal cancer

تعداد نتایج: 915324  

2013
CAROL O’CALLAGHAN LIAM J. FANNING AILEEN HOUSTON ORLA P. BARRY

Oesophageal cancer is an aggressive tumour which responds poorly to both chemotherapy and radiation therapy and has a poor prognosis. Thus, a greater understanding of the biology of oesophageal cancer is needed in order to identify novel therapeutic targets. Among these targets p38 MAPK isoforms are becoming increasingly important for a variety of cellular functions. The physiological functions...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2004
G Chong D Cunningham

The optimal management of localised oesophageal cancer remains controversial. Indeed, currently utilised strategies are clearly unsatisfactory, given that most randomised trials report overall 5-year survivals of 20% or less for patients undergoing surgical resection. The rationale behind preoperative chemotherapy is two-fold: (i) to downstage or downsize the primary tumour in order to ensure c...

Journal: :The Indian journal of surgery 2009
Daniel K H Tong Simon Law

Oesophageal cancer is a disease of dismal prognosis. There are variations of epidemiology among different ethnic groups and geographic regions. India is a country with high incidence. This can be attributed to the interplay between environmental, dietary factors and life-style of the population of the country. Optimal therapeutic strategy for patients with oesophageal cancer demands individual ...

Journal: :iranian journal of public health 0
a sadjadi mj zahedi s darvish moghadam m nouraie m alimohammadian a ghorbani

background: cancer is the second most common cause of non-accidental death in iran. geographical, racial and habitual differences have led to the variation in the incidence of cancer in different regions of this country. this study was performed to determine the incidence of cancer in the kerman province, central iran. methods: all newly diagnosed cases of cancer in the kerman province were rec...

2014
Stanisław Głuszek Marta Kot Bartłomiej Kotucha Renata Stępień Dorota Kozieł

INTRODUCTION Cancer located in the oesophagus and gastroesophageal junction is a complex clinical problem and the results of its treatment still remain unsatisfactory. The objective of the study was the clinical analysis of a group of patients with cancer of the oesophagus or gastroesophageal junction, who received combined medical and surgical treatment. MATERIAL AND METHODS The analysis was...

Journal: :Annali italiani di chirurgia 2013
Giovanni Leuzzi Alfredo Cesario Stefano Margaritora Anna Mariantonia Parisi Venanzio Porziella Elisa Meacci Maria Letizia Vita Maria Teresa Congedo Marco Chiappetta Pierluigi Granone

Skeletal muscle metastasis is a very rare event in patients with oesophageal cancer. We herein report and discuss a case of a 65 years old man with history of gastro-esophageal reflux disease referred to our department for pyrosis associated to persistent low back pain. Oesophageal endoscopy and transesophageal endo-sonography showed a tumour localized in the lower third of the esophagus, histo...

2016
Puya Gharahkhani Rebecca C Fitzgerald Thomas L Vaughan Claire Palles Ines Gockel Ian Tomlinson Matthew F Buas Andrea May Christian Gerges Mario Anders Jessica Becker Nicole Kreuser Tania Noder Marino Venerito Lothar Veits Thomas Schmidt Hendrik Manner Claudia Schmidt Timo Hess Anne C Böhmer Jakob R Izbicki Arnulf H Hölscher Hauke Lang Dietmar Lorenz Brigitte Schumacher Andreas Hackelsberger Rupert Mayershofer Oliver Pech Yogesh Vashist Katja Ott Michael Vieth Josef Weismüller Markus M Nöthen Stephen Attwood Hugh Barr Laura Chegwidden John de Caestecker Rebecca Harrison Sharon B Love David MacDonald Paul Moayyedi Hans Prenen R G Peter Watson Prasad G Iyer Lesley A Anderson Leslie Bernstein Wong-Ho Chow Laura J Hardie Jesper Lagergren Geoffrey Liu Harvey A Risch Anna H Wu Weimin Ye Nigel C Bird Nicholas J Shaheen Marilie D Gammon Douglas A Corley Carlos Caldas Susanne Moebus Michael Knapp Wilbert H M Peters Horst Neuhaus Thomas Rösch Christian Ell Stuart MacGregor Paul Pharoah David C Whiteman Janusz Jankowski Johannes Schumacher

BACKGROUND Oesophageal adenocarcinoma represents one of the fastest rising cancers in high-income countries. Barrett's oesophagus is the premalignant precursor of oesophageal adenocarcinoma. However, only a few patients with Barrett's oesophagus develop adenocarcinoma, which complicates clinical management in the absence of valid predictors. Within an international consortium investigating the ...

Journal: :European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2014
Geun Dong Lee Yong-Hee Kim Se Hoon Choi Hyeong Ryul Kim Dong Kwan Kim Seung-Il Park

OBJECTIVES Gastric conduit cancer (GCC), which is a carcinoma that arises in the gastric conduit after oesophagectomy, often negatively affects long-term survivors of oesophageal cancer. The aim of this study was to evaluate the incidence and clinical implications of GCC. METHODS We reviewed data for 863 patients who underwent an oesophagectomy and a reconstruction of the gastric conduit from...

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