Inhibin production has been demonstrated in malignant epithelial ovarian tumours, but secretion of inhibins by benign cystadenoma has not yet been reported. The present study evaluated the concentrations of inhibin A and inhibin B and the relationship with oestradiol and nitric oxide metabolites in fluid collected from benign ovarian serous cystadenomas (n = 15). In addition, follicular fluid s...

OBJECTIVE A rise in oestrogen in the preovulatory phase produces a GnRH-induced luteinising hormone surge. Oestrogen receptors are not found on GnRH neurons but these are present on kisspeptin neurons. That led us to hypothesise that serum kisspeptin levels may vary during various phases of the menstrual cycle in relation to serum oestradiol. METHODS Thirty female students, 18-25 years old, S...

Reproductive inefficiency is one of the most important and cost limiting factor to profitable small ruminant production in tropics. The aim this study was evaluate influence breed on oestrus response, reproductive oestradiol 17 β profiles Red Sokoto (RS), Sahelian (SH) West African Dwarf (WAD) goats following synchronisation with prostaglandin F2α (PGF2α). Thirty (N = 30) apparently healthy; RS...

Plasma concentrations of ethynyl oestradiol and norethindrone in women were measured by radioimmunoassays after oral administration of 50 microng and 1000 microng respectively. The maximum values were obtained 1 h after administration. The calculated half-life was 6 1/2 h for ethynyl oestradiol and 7 h for norethindrone. At most 2-3% of the administered dose was present in the plasma at 1 h and...

BACKGROUND AND OBJECTIVE Kisspeptin stimulates hypothalamic GnRH secretion resulting in gonadotrophin release and has potential as a future therapeutic. Chronic subcutaneous infusion of kisspeptin via a pump (similar to an insulin pump) may provide an alternative route of administration in the future. We investigated for the first time in humans, the gonadotrophin response to subcutaneous (SC) ...

OBJECTIVE To explore relations between biochemical markers of bone turnover, indices of nutritional status, and serum oestradiol concentration in women distance runners. METHODS Thirty three women distance runners of mean age (SD) 27.2 (1.8) years participated. Eighteen were defined as eumenorrhoeic, nine as amenorrhoeic, and six as oligomenorrhoeic. Mean (SD) running distance was 47.6 (22.4)...

Aim: Estrogens and progesterone are essential for breast development in women. Paradoxically they promote the of cancer, through stimulation proliferation cells by action hormone receptors. In Côte d'Ivoire, more than half all diagnosed cases cancer hormone-dependent. Because link between female hormones consideration certain factors, such as period influence (estrogen progesterone) well their ...

Changes in sexual behavior and progesterone, oestrone, oestradiol, testosterone and androstenedione concentrations have been studied in the follicular fluid of 25 pseudopregnant rabbits on Days 6, 9, 12, 15 and 18. The sexual behavior score seemed to rise at the end of pseudopregnancy and follicular steroid levels were higher on Days 6 and 18 of pseudopregnancy than on Days 9, 12 or 15. The gen...

Menopause refers to the cessation menstruation. It is a counterpart of menarche which marks the beginning of menstruation. The current understanding of the physiology of menopause is that there is a depletion of primary Oocytes in the ovary by atresia as an effect of aging coupled with decreased sensitivity of the remaining Oocyte to Gonadotropins. This is then reflected as a decrease in the le...

Earlier studies have demonstrated that phenol UDP-glucuronosyltransferase (UGT) activity is up-regulated by pregnant mare's serum gonadotropin (PMSG) in rat ovary, but not liver. This phenomenon was investigated in more detail in the present study. Ovaries and livers of immature rats, rats synchronized with respect to their preovulatory and corpus luteal phases by treatment with PMSG, and matur...