Objectives: Insulin resistance is a major pathophysiology in polycystic ovary syndrome (PCOS), and assessment of insulin sensitivity is important. Various insulin sensitivity indices from fasting state or oral glucose tolerance test (OGTT) have been compared with euglycemic hyperinsulinemic clamp. We aimed to evaluate the usefulness of these indices in young Korean women with PCOS. Methods: Eug...

Routine detection of health parameters is desirable to recognize the early onset metabolic diseases (e.g., diabetes mellitus) and personalize their treatment. Promising are non-invasive, affordable portable technologies, such as breath sensors. Yet, selective monitoring markers acetone for lipolysis) with sensors track changes that can reveal disease-related abnormalities remains challenging. H...

The new diagnostic criteria recommended by the American Diabetes Association (ADA) will only detect diabetic patients with fasting hyperglycemia, and leave patients with isolated post-challenge hyperglycemia (IPCH) and imparied glucose tolerance (IGT) unidentified. The WHO recommends that all those with abnormal fasting glucose should undergo the oral glucose tolerance test (OGTT) to exclude th...

The relationship between diabetes mellitus (DM) and cardiovascular disease is well recognized.1,2 The oral glucose tolerance test (OGTT) (World Health Organization [WHO] 1985 and 1999)3,4 and fasting plasma glucose (FBG) (American Diabetes Association [ADA] 1997 and 2003)5 are both methods for diagnosing DM. The agreement between these methods has been questioned in several epidemiological stud...

UNLABELLED BACKGROUND Plasma glucose levels are important measures in medical care and research, and are often obtained from oral glucose tolerance tests (OGTT) with repeated measurements over 2-3  hours. It is common practice to use simple summary measures of OGTT curves. However, different OGTT curves can yield similar summary measures, and information of physiological or clinical interest...

This study aimed to investigate the utility of first trimester HbA1c in predicting gestational diabetes mellitus (GDM) obese women with Grade II–III obesity. was measured during 160 women. A 75g oral glucose tolerance test (OGTT) performed between 24–28 weeks gestation and GDM diagnosed by WHO criteria. The prevalence 24%. An ≤28mmol/mol had 100% negative predictive value for GDM. ≥33mmol/mol a...

Abstract Background/Introduction Oxidative stress plays an important role in the pathogenesis of type 2 diabetes mellitus. Purpose We aimed to investigate oxidative and nitrites/nitrates concentrations at baseline during postprandial hyperglycaemia 40 first-degree relatives (FDR) diabetic patients with normal oral glucose test (OGTT), subjects abnormal OGTT (dysglycaemic) 20 without parental hi...

Objectives: A screening tool for Cystic Fibrosis Diabetes (CFD) is in use at the Norfolk and Norwich University Hospital (NNUH) to improve cost-effectiveness ensure appropriate allocation of limited time resources within CF team. The involves initial using 3-point oral glucose tolerance testing (OGTT) alongside HbA1c. When this not possible, HbA1c used isolation highlight patients additional mo...

RESEARCHDESIGNANDMETHODSdWe selected 522 participants enrolled into the Study of Women, Infant Feeding, and Type 2 Diabetes (SWIFT), a prospective observational cohort study of Kaiser Permanente Northern California members diagnosed with GDM using the 3-h 100-g OGTT by the Carpenter and Coustan criteria. Women were classified as normal, prediabetes, or diabetes according to American Diabetes As...

A close relations ship exists between hypertension and diabetes it is necessary to diagnose diabetes or risk of diabetes as early as possible avoid complication. The present study was conducted in 100 newly diagnosed patients of hypertension. These patients were meticulously studied for risk factors for hypertension, clinical presentation, ECG and biochemical investigation. These patients were ...