نتایج جستجو برای: oncomirs
تعداد نتایج: 134 فیلتر نتایج به سال:
Purpose: MicroRNAs (miRNAs) post-transcriptionally regulate hundreds of gene targets involved in tumorigenesis thereby controlling vital biological processes, including cellular proliferation, di erentiation and apoptosis. MiRNA pro ling is an emerging tool for the potential early detection of a variety of malignancies. is study was conducyed to assess the feasibility and methodological robustn...
Purpose:miRNAs can act as oncomirs or tumor-suppressormiRs in cancer. This studywas undertaken to investigate the status and role of miR-34b in prostate cancer. Experimental Design: Profiling of miR-34b was carried out in human prostate cancer cell lines and clinical samples by quantitative real-time PCR and in situ hybridization. Statistical analyses were done to assess diagnostic/prognostic p...
1Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, USA Correspondence: Frank J Slack, Department of Molecular, Cellular and Developmental Biology, Yale University, PO Box 208103, New Haven, Connecticut 06520, USA. E-mail: [email protected] Various treatment options are available for hepatocellular carcinoma (HCC); however, the overwhelming ...
Cutaneous squamous cell carcinoma (cSCC) is a malignant neoplasm of the skin resulting from accumulation somatic mutations due to solar radiation. cSCC one fastest increasing malignancies, and it represents particular problem among immunosuppressed individuals. MicroRNAs are short noncoding RNAs that regulate expression protein-coding genes at post-transcriptional level. In this study, we ident...
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