ABOUT THIS RESEARCH BRIEF This ASPE Research Brief was written by Brian Goesling and Joanne Lee of Mathematica Policy Research as part of an ongoing systematic review of the teen pregnancy prevention literature. Since 2009, Mathematica and its partner, Child Trends, have conducted the Teen Pregnancy Prevention Evidence Review under contract with HHS. The review aims to identify, assess, and rat...

OBJECTIVE To evaluate the effects of acupuncture on clinical pregnancy rates for women undergoing ET. DESIGN Single-blind, randomized controlled trial using a noninvasive sham acupuncture control. SETTING Repromed, The Reproductive Medicine Unit of The University of Adelaide. PATIENT(S) Women undergoing IVF. INTERVENTION(S) Women were randomly allocated to acupuncture or noninvasive sha...

BACKGROUND Initial low maternal serum β-human chorionic gonadotropin (β-hCG) is a good predictor of early pregnancy demise. Our objective was to determine its predictive value in determining the long-term outcome in ICSI pregnancies. METHODS A retrospective cohort study was designed at the Saudi Center for Assisted Reproduction. Two hundred and sixty-one women with ICSI pregnancies were follo...

BACKGROUND The pregnancy outcome of the unicornuate uterus is associated with an increased risk of miscarriage, cervical incompetence, and a number of obstetric complications. However, at present, there is no accepted treatment method for women with unicornuate uterus, other than expectant measures. The aim of this study was to evaluate the reproductive outcome of transcervical uterine incision...

Background. Discussion of the incidence of molar pregnancy and ectopic pregnancy. Role of salpingostomy and special considerations for postoperative care. Case. The patient is a 29-year-old G7P4 who presented with vaginal bleeding in the first trimester and was initially thought to have a spontaneous abortion. Ultrasound was performed due to ongoing symptoms and an adnexal mass was noted. She u...

BACKGROUND The role of insulin-like growth factor (IGF)-I in breast cancer remains controversial, despite numerous reports on the association of the hormone with breast cancer or high-risk mammographic densities. We hypothesized that exposure to elevated IGF-I during early pregnancy, a period characterized by intense cell proliferation in the breasts and in the presence of high concentrations o...

UNLABELLED SUMMARY QUESTION: Is vaginal progesterone gel equivalent to vaginal micronized progesterone tablets concerning ongoing pregnancy rate and superior concerning patient convenience when used for luteal support after IVF/ICSI? SUMMARY ANSWER Equivalence of treatments in terms of ongoing live intrauterine pregnancy rate has not been demonstrated; the 95% confidence interval (CI) for the...

OBJECTIVE To assess the effects of ultrasonographically detected subchorionic hematomas on pregnancy outcomes in patients with vaginal bleeding within the first half of pregnancy. MATERIAL AND METHODS Patients diagnosed with threatened abortion due to painless vaginal bleeding and who were followed up in an in-patient service during the first vaginal bleeding between January 2009 and December...

OBJECTIVE To investigate optimal timing of elective repeat caesarean section among low-risk pregnant women with prior caesarean section in a multicountry sample from largely low- and middle-income countries. DESIGN Secondary analysis of a cross-sectional study. SETTING Twenty-nine countries from the World Health Organization Multicountry Survey on Maternal and Newborn Health. POPULATION 2...

Background Gonadotropin-releasing hormone agonists (GnRH-a) was increasingly used for triggering oocyte maturationfor the prevention of ovarian hyperstimulation syndrome. Studies suggest that GnRH-a might be used as a better trigger agent since it causes both Luteinizing hormone and follicle stimulating hormone release from a physiologic natural cycle. Objective The aim of this study was to e...