Few data are available concerning single Ca channel properties in inner ear hair cells and particularly none in vestibular type I hair cells. By using the cell-attached configuration of the patch-clamp technique in combination with the semicircular canal crista slice preparation, we determined the elementary properties of voltage-dependent Ca channels in chicken embryo type I and type II hair c...

This study seeks to empirically investigate specific security characteristics of both open source software and proprietary software. Operating system software vulnerability data spanning several years are collected and analyzed to determine if significant differences exist in terms of inter-arrival times of published vulnerabilities and patch releases. Open source software is only marginally qu...

Glycine-activated single-channel currents in rat central neurones were recorded using the outside-out mode of the patch-clamp technique. The unitary conductance of the current was 21 pS. The current evoked by 10 microM glycine had a mean burst duration of 47.8 (2.6) ms and open probability of 0.09 (0.016). Halothane (1 mM) increased the open probability to 0.19 (0.03) without changing either un...

Few data are available concerning single Ca channel properties in inner ear hair cells, and particularly none in vestibular type I hair cells. By using the cell-attached configuration of the patch-clamp technique in combination with the semicircular canal crista slice preparation, we determined the elementary properties of voltage-dependent Ca channels in chicken embryo type I and type II hair ...

Experiments with inside-out patches excised from pancreatic B-cells have yielded evidence that mitochondria are often contained in the cytoplasmic plug protruding into the tip of patch pipette. When intact B-cells were loaded with the fluorescent mitochondrial stain, rhodamine 123, and membrane patches excised from these cells, a green fluorescence could be observed in the lumen at the tip of t...

Marine protected areas are commonly seen as the most effective strategy for protecting mangroves from external human pressures but little is known about the role of public land-tenure contexts (dense settlements, agricultural or range lands and wild anthromes) on clearing rates, patch properties, and ecological condition. We addressed the following questions using a peri-urban to wild gradient ...