Calorie restriction (CR) and fasting affect lifespan, disease susceptibility response to acute injury across multiple animal models, including ischaemic injuries such as myocardial infarction or kidney hypoxia. The cargo function of circulating extracellular vesicles (EV) respond changes in host physiology, exercise, injury, other interventions. Thus, we hypothesised that EVs induced following ...

BACKGROUND Gestational diabetes mellitus (GDM) is associated with increased risk of fetal macrosomia and shoulder dystocia. However, not all women with GDM and fetal macrosomia have shoulder dystocia. AIMS To identify the risk factors for shoulder dystocia in women with gestational diabetes using data from women recruited into the routine care group of the ACHOIS trial. METHODS A secondary ...

muslims all over the world fast in the holy month of ramadan. fasting means abstinence from drinking any liquids, eating, smoking and taking anything parenterally.  it is intermittent in nature from the start of dawn to end at dusk. fasting has various physiological effects on different biological parameters of the human body. previous studies that look at effect of ramadan fasting on blood pre...

Impaired wound healing is a frequent problem in diabetes. Hyperglycemia may be an operative mechanism, but a link between glycemic control and wound healing has never been established. Wounds in db/db mice have been extensively studied. This study was undertaken to see if plasma glucose was a predictor of wound healing. An excisional wound was made (149 db/db mice). Wound closure was studied ve...

The aims of this study were to produce mesobiliverdin IXα, an analog of anti-inflammatory biliverdin IXα, and to test its ability to enhance rat pancreatic islet yield for allograft transplantation into diabetic recipients. Mesobiliverdin IXα was synthesized from phycocyanobilin derived from cyanobacteria, and its identity and purity were analyzed by chromatographic and spectroscopic methods. M...

Meeting patients' nutritional requirements and preventing malnutrition is a challenge following major surgical procedures. The role of ghrelin in nutritional recovery after non-gastrointestinal major surgery is unknown. We used coronary artery bypass grafting (CABG) as an example of anticipated good recovery post major surgery.Seventeen patients undergoing CABG (mean +/- SEM: 70.1 +/- 2.2 yrs, ...

ramadan is a holy month for muslims and fasting in this month is the rule for any healthy matured person. nutritional and behavioral changes occurred during ramadan fasting may lead to several physiological change, such as blood pressure (2). studies evaluated the effects of ramadan fasting on blood pressure in hypertensive patients, are scarce and reported inadequate results. in this paper a s...