نتایج جستجو برای: opiate addiction

تعداد نتایج: 26705  

Journal: :Biological psychiatry 2004
Steven D Forman George G Dougherty B J Casey Greg J Siegle Todd S Braver Deanna M Barch V Andrew Stenger Charlene Wick-Hull Liubomir A Pisarov Emily Lorensen

BACKGROUND Healthy individuals performing response suppression tasks activate anterior cingulate cortex with occurrence of false alarm error responses to nontargets. Fundamental questions include whether this error-related activation provides a signal contributing to behavioral control and, given generally poorer performance on such tasks by addicts, whether this signal is disrupted in addictio...

2012
Jaung-Geng Lin Yuan-Yu Chan Yi-Hung Chen

Acupuncture is an accepted treatment worldwide for various clinical conditions, and the effects of acupuncture on opiate addiction have been investigated in many clinical trials. The present review systematically analyzed data from randomized clinical trials published in Chinese and English since 1970. We found that the majority agreed on the efficacy of acupuncture as a strategy for the treatm...

Journal: :iranian rehabilitation journal 0
bahareh amirabadi shahid beheshti university of medical sciences, tehran, iran. neda alibeigi university of social welfare and rehabilitation sciences, tehran, iran. mohammad nikbakht shahid beheshti university of medical sciences, tehran, iran. omid massah substance abuse and dependence research center, university of social welfare & rehabilitation sciences, tehran, iran. ali farhoudian substance abuse and dependence research center, university of social welfare & rehabilitation sciences, tehran, iran. younes doostian university of social welfare & rehabilitation sciences, tehran, iran.

objectives: according to the gateway drug theory, tobacco use is a predisposing factor for future substance abuse. this study was conducted to compare nicotine and opiate dependents to identify the differences between their personality traits and psychopathology that makes them turn to other substances after cigarette smoking. methods: a causal-comparative study was conducted. three groups were...

Journal: :Neuroscience letters 2003
Desmond J Smith Tarek A Leil Xin Liu

Tolerance is an important component of opiate addiction, but the molecular basis for this phenomenon remains obscure. Here, we report that mice lacking neurotrophin-4 (NT4) display substantially reduced tolerance to morphine compared to wild-type. However, there were no deficits in sensitization and withdrawal, other behaviors relevant to drug addiction. Since NT4 knockout mice also show abnorm...

Journal: :Journal of General Internal Medicine 2002

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2005
Angelo Contarino Francesco Papaleo

The negative affective symptoms of opiate withdrawal powerfully motivate drug-seeking behavior and may trigger relapse to heroin abuse. To date, no medications exist that effectively relieve the negative affective symptoms of opiate withdrawal. The corticotropin-releasing factor (CRF) system has been hypothesized to mediate the motivational effects of drug dependence. The CRF signal is transmit...

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