نتایج جستجو برای: optical microscope

تعداد نتایج: 306227  

Journal: :BioTechniques 2000
K W Dunn E Wang

Refinements in design have simplified confocal microscopy to the extent that it has become a standard research tool in cell biology. However, as confocal microscopes have become more powerful, they have also become more demanding of their optical components. In fact, optical aberrations that cause subtle defects in image quality in wide-field microscopy can have devastating effects in confocal ...

2013
Yuki Suzuki Nobuaki Sakai Aiko Yoshida Yoshitsugu Uekusa Akira Yagi Yuka Imaoka Shuichi Ito Koichi Karaki Kunio Takeyasu

A hybrid atomic force microscopy (AFM)-optical fluorescence microscopy is a powerful tool for investigating cellular morphologies and events. However, the slow data acquisition rates of the conventional AFM unit of the hybrid system limit the visualization of structural changes during cellular events. Therefore, high-speed AFM units equipped with an optical/fluorescence detection device have be...

Journal: :Applied optics 2002
F Dubois C Minetti O Monnom C Yourassowsky J C Legros P Kischel

We describe the implementation of the automatic spatial-frequency-selection filter for recognition of patterns obtained with a digital holographic microscope working with a partially coherent source. The microscope provides the complex-optical-amplitude field that allows a refocusing plane-by-plane of the sample under investigation by numerical computation of the optical propagation. By inserti...

Journal: :Optics express 2009
Li Li Konstantin Maslov Geng Ku Lihong V Wang

Photoacoustic microscopy is predominantly sensitive to optical absorption, while optical coherence tomography relies on optical backscattering. Integrating their complementary contrasts can provide comprehensive information about biological tissue. We have developed a dual-modality microscope that combines the two for studying microcirculation. Three-dimensional imaging of microvasculature and ...

Journal: :Nanomaterials 2017
Timur Sh Atabaev Jong Ho Lee Yong Cheol Shin Dong-Wook Han Ki Seok Choo Ung Bae Jeon Jae Yeon Hwang Jeong A Yeom Hyung-Kook Kim Yoon-Hwae Hwang

Nanoprobes with multimodal functionality have attracted significant interest recently because of their potential applications in nanomedicine. This paper reports the successful development of lanthanide-doped Y₂O₃ nanoprobes for potential applications in optical and magnetic resonance (MR) imaging. The morphology, structural, and optical properties of these nanoprobes were characterized by tran...

2017
K. Sathiyamoorthy Eric M. Strohm Michael C. Kolios

We have developed a low-cost, non-contact, multispectral photoacoustic microscope system to study the functional parameters of cellular choromophores. The system uses low power continuous wave lasers and a photoacoustic sensor made of a kHz microphone coupled to a resonant chamber. Methemoglobin has relatively high optical absorption at 500 nm and 630 nm. Moreover, it has an almost the same opt...

Journal: :Acta medico-historica adriatica : AMHA 2015
Giovanni Ponti Umberto Muscatello Markos Sgantzos

For a long period the scientists did not recognized the potentialities of the compound microscope in medicine. Only few scientists recognized the potentialities of the microscope for the medicine; among them G. Campani who proposed the utilization of his microscope to investigate the skin lesions directly on the patient. The proposal was illustrated in a letter Acta Eruditorum of 1686. The rece...

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